Influenza viruses cause annual epidemics and occasional pandemics of respiratory tract
infections that produce a wide spectrum of clinical disease severity in humans. The novel …

With the expanding use of molecular assays, viral pathogens are increasingly recognized
among critically ill adult patients with community-acquired severe respiratory illness; studies …

Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …

Background Remdesivir improves clinical outcomes in patients hospitalized with moderate-
to-severe coronavirus disease 2019 (Covid-19). Whether the use of remdesivir in …

Background No therapeutics have yet been proven effective for the treatment of severe
illness caused by SARS-CoV-2. Methods We conducted a randomized, controlled, open …

These clinical practice guidelines are an update of the guidelines published by the
Infectious Diseases Society of America (IDSA) in 2009, prior to the 2009 H1N1 influenza …

Purpose Severe community-acquired pneumonia (sCAP) is associated with high morbidity
and mortality, and whilst European and non-European guidelines are available for …

SARS-CoV-2 is causing an increasing number of deaths worldwide because no effective
treatment is currently available. Remdesivir has shown in vitro activity against coronaviruses …

Community-acquired pneumonia causes great mortality and morbidity and high costs
worldwide. Empirical selection of antibiotic treatment is the cornerstone of management of …

Background Despite widespread use, questions remain about the efficacy of oseltamivir in
the treatment of influenza. We aimed to do an individual patient data meta-analysis for all …