Oral submucous fibrosis: etiological mechanism, malignant transformation, therapeutic approaches and targets
X Qin, Y Ning, L Zhou, Y Zhu - International journal of molecular sciences, 2023 - mdpi.com
Oral submucosal fibrosis (OSF) is a chronic, progressive and potentially malignant oral
disorder with a high regional incidence and malignant rate. With the development of the …
disorder with a high regional incidence and malignant rate. With the development of the …
MicroRNAs as modulators of oral tumorigenesis—A focused review
Oral cancers constitute the majority of head and neck tumors, with a relatively high incidence
and poor survival rate in develo** countries. While the five-year survival rates of the oral …
and poor survival rate in develo** countries. While the five-year survival rates of the oral …
Analysis of oral lichen planus severity on micro‐RNA linked with malignant transformation risks
A Polizzi, S Santonocito, A Distefano… - Oral …, 2024 - Wiley Online Library
Objective The present study evaluated the oral tissue expression of micro‐RNA (miRNAs)
linked to the potential malignant evolution of oral lichen planus (OLP). Furthermore, the …
linked to the potential malignant evolution of oral lichen planus (OLP). Furthermore, the …
miRNAs as biomarkers for diagnosing and predicting survival of head and neck squamous cell carcinoma patients
I Piotrowski, X Zhu, TD Saccon, S Ashiqueali… - Cancers, 2021 - mdpi.com
Simple Summary Head and Neck Squamous Cell Carcinoma (HNSCC) is the sixth most
common cancer worldwide. It arises from the epithelium of the upper aerodigestive tract …
common cancer worldwide. It arises from the epithelium of the upper aerodigestive tract …
Natural compounds targeting miRNAs: a novel approach in oral cancer therapy
Oral cancer (OC) is a significant global health issue, with high rates of both mortality and
morbidity. Conventional treatments, including surgery, radiation, and chemotherapy, are …
morbidity. Conventional treatments, including surgery, radiation, and chemotherapy, are …
Non-coding RNAs in oral cancer: emerging roles and clinical applications
S Dey, B Biswas, A Manoj Appadan, J Shah, JK Pal… - Cancers, 2023 - mdpi.com
Simple Summary Oral cancer (OC) is one of the most prevalent cancers in the world. Despite
improvements in therapies, OC still has a poor survival rate of about 50%, with metastasis …
improvements in therapies, OC still has a poor survival rate of about 50%, with metastasis …
Head and neck cancers are not alike when tarred with the same brush: An epigenetic perspective from the cancerization field to prognosis
Simple Summary Squamous cell carcinomas affect different head and neck subsites and,
although these tumors arise from the same epithelial lining and share risk factors, they differ …
although these tumors arise from the same epithelial lining and share risk factors, they differ …
[HTML][HTML] miR-1293, a candidate for miRNA-based cancer therapeutics, simultaneously targets BRD4 and the DNA repair pathway
Y Takagawa, Y Gen, T Muramatsu, K Tanimoto… - Molecular Therapy, 2020 - cell.com
BRD4, a member of the bromodomain and extra-terminal domain (BET) protein family, plays
a role in the organization of super-enhancers and transcriptional activation of oncogenes in …
a role in the organization of super-enhancers and transcriptional activation of oncogenes in …
Nanoparticulate strategies for the delivery of miRNA mimics and inhibitors in anticancer therapy and its potential utility in oral submucous fibrosis
MicroRNAs (miRNAs) are naturally occurring noncoding RNAs with multiple functionalities.
They are dysregulated in several conditions and can serve as disease biomarkers …
They are dysregulated in several conditions and can serve as disease biomarkers …
Assessing miRNAs profile expression as a risk stratification biomarker in oral potentially malignant disorders: A systematic review
Objectives This paper aims to systematically review current findings on altered expression of
miRNAs in OPMDs and whether they can be used as risk stratification biomarkers. Methods …
miRNAs in OPMDs and whether they can be used as risk stratification biomarkers. Methods …