Organic food: buying more safety or just peace of mind? A critical review of the literature

F Magkos, F Arvaniti, A Zampelas - Critical reviews in food science …, 2006 - Taylor & Francis
Consumer concern over the quality and safety of conventional food has intensified in recent
years, and primarily drives the increasing demand for organically grown food, which is …

Apoptosis as a novel target for cancer chemoprevention

SY Sun, N Hail Jr, R Lotan - Journal of the national cancer …, 2004 - academic.oup.com
Cancer chemopreventive agents are typically natural products or their synthetic analogs that
inhibit the transformation of normal cells to premalignant cells or the progression of …

Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production

N Li, K Ragheb, G Lawler, J Sturgis, B Rajwa… - Journal of Biological …, 2003 - ASBMB
Inhibition of mitochondrial respiratory chain complex I by rotenone had been found to induce
cell death in a variety of cells. However, the mechanism is still elusive. Because reactive …

Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype

B Kumar, S Koul, L Khandrika, RB Meacham, HK Koul - Cancer research, 2008 - AACR
Reactive oxygen species (ROS) and the coupled oxidative stress have been associated with
tumor formation. Several studies suggested that ROS can act as secondary messengers and …

Natural product pesticides: their development, delivery and use against insect vectors

R S. Mann, P E. Kaufman - Mini-reviews in organic chemistry, 2012 - benthamdirect.com
Natural chemicals have considerable potential for vector management because these
chemicals are safer than conventional insecticides on account of their rapid environmental …

Neurotoxicant-induced animal models of Parkinson's disease: understanding the role of rotenone, maneb and paraquat in neurodegeneration

VN Uversky - Cell and tissue research, 2004 - Springer
The etiologic basis of Parkinson's disease (PD), the second most common age-related
neurodegenerative disorder, is unknown. Recent epidemiological and experimental studies …

Differentiation of mesenchymal stem cells towards a nucleus pulposus-like phenotype in vitro: implications for cell-based transplantation therapy

MV Risbud, TJ Albert, A Guttapalli, EJ Vresilovic… - Spine, 2004 - journals.lww.com
Objective. Because mesenchymal stem cells can differentiate into chondrocyte-like cells, we
ask the question, can mesenchymal stem cells commit to the nucleus pulposus phenotype …

Zerumbone, a Southeast Asian ginger sesquiterpene, markedly suppresses free radical generation, proinflammatory protein production, and cancer cell proliferation …

A Murakami, D Takahashi, T Kinoshita… - …, 2002 - academic.oup.com
Zerumbone (ZER), a sesquiterpene from the edible plant Zingiber zerumbet Smith, has
recently been found to suppress tumor promoter 12-O-tetradecanoylphorbol-13-acetate …

Rotenone model of Parkinson disease: multiple brain mitochondria dysfunctions after short term systemic rotenone intoxication

A Panov, S Dikalov, N Shalbuyeva, G Taylor… - Journal of Biological …, 2005 - ASBMB
Chronic infusion of rotenone (Rot) to Lewis rats reproduces many features of Parkinson
disease. Rot (3 mg/kg/day) was infused subcutaneously to male Lewis rats for 6 days using …

Neuroprotective Effects of Hesperidin, a Plant Flavanone, on Rotenone‐Induced Oxidative Stress and Apoptosis in a Cellular Model for Parkinson's Disease

K Tamilselvam, N Braidy… - Oxidative medicine …, 2013 - Wiley Online Library
Rotenone a widely used pesticide that inhibits mitochondrial complex I has been used to
investigate the pathobiology of PD both in vitro and in vivo. Studies have shown that the …