The γ-lactam moiety is present in a large number of natural and non-natural biologically
active compounds. The range of biological activities covered by these compounds is very …

Stress proteins (SPs) including heat-shock proteins (HSPs), RNA chaperones, and ER
associated stress proteins are molecular chaperones essential for cellular homeostasis. The …

Oceans have borne most of the biological activities on our planet. A number of biologically
active compounds with varying degrees of action, such as anti-tumor, anti-cancer, anti …

Biosynthesis of natural products by microbial iterative hybrid PKS–NRPS - RSC Advances (RSC
Publishing) DOI:10.1039/C3RA42661K Royal Society of Chemistry View PDF VersionPrevious …

The 60 kDa heat shock protein (Hsp60) is classically known as a mitochondrial chaperonin
protein working together with co-chaperonin 10 kDa heat shock protein (Hsp10). This …

In recent years, the search for novel natural compounds with bioactive properties has
received a remarkable boost in view of their possible pharmaceutical exploitation. In this …

The Knoevenagel condensation reaction is a prominent organic reaction commonly being
utilized in the total synthesis of natural and biologically potent products as a vital and …

Neurodegenerative diseases and spinal cord injury affect approximately 50 million people
worldwide, bringing the total healthcare cost to over 600 billion dollars per year. Nervous …

The inadequate vascularization seen in fast-growing solid tumors gives rise to hypoxic
areas, fostering specific changes in gene expression that bolster tumor cell survival and …

In recent years, published reviews clearly indicate the tremendous potential of marine
microorganisms as a source of new pharmaceuticals [1–9]. Rather than repeat a …