BFVD—a large repository of predicted viral protein structures

RS Kim, E Levy Karin, M Mirdita, R Chikhi… - Nucleic Acids …, 2025 - academic.oup.com
Abstract The AlphaFold Protein Structure Database (AFDB) is the largest repository of
accurately predicted structures with taxonomic labels. Despite providing predictions for over …

Diversity, evolution, and emergence of fish viruses

VA Costa, EC Holmes - Journal of Virology, 2024 - Am Soc Microbiol
The production of aquatic animals has more than doubled over the last 50 years and is
anticipated to continually increase. While fish are recognized as a valuable and sustainable …

Multiple protein structure alignment at scale with FoldMason

CLM Gilchrist, M Mirdita, M Steinegger - bioRxiv, 2024 - biorxiv.org
Protein structure is conserved beyond sequence, making multiple structural alignment
(MSTA) essential for analyzing distantly related proteins. Computational prediction methods …

The 3rd anniversary of Frontiers in Virology: aiming to consolidate the virus research

A Adachi, T Koma, M Nomaguchi - Frontiers in Virology, 2024 - frontiersin.org
mutability and its wild-bird origin. Experts are really anxious about other terrible
influenzapandemics by new type viruses. About 40 years ago, we also encountered another …

Unicore enables scalable and accurate phylogenetic reconstruction with structural core genes

D Kim, S Park, M Steinegger - bioRxiv, 2024 - biorxiv.org
The analysis of single-copy core genes, common to most members of a clade, is important
for key tasks in biology including phylogenetic reconstruction and assessing genome …

[HTML][HTML] Using structure prediction of negative sense RNA virus nucleoproteins to assess evolutionary relationships

KR Sabsay, AJW Te Velthuis - bioRxiv, 2024 - ncbi.nlm.nih.gov
Negative sense RNA viruses (NSV) include some of the most detrimental human pathogens,
including the influenza, Ebola and measles viruses. NSV genomes consist of one or multiple …

Tunicate metatranscriptomes reveal ancient virus-host co-divergence and inter-order recombination in the evolutionary history of disease-causing viruses

ME Petrone, J Grove, R Parry, K Van Brussel… - bioRxiv, 2024 - biorxiv.org
Tunicates are a key transitional taxon in animal evolution as the closest extant invertebrate
relatives of the vertebrates. Their viruses may also reflect this transitional state. Yet, it is not …

Viro3D: a comprehensive database of virus protein structure predictions

U Litvin, S Lytras, A Jack, DL Robertson, J Grove… - bioRxiv, 2024 - biorxiv.org
Viruses are intracellular parasites of organisms from all domains of life. They infect and
cause disease in humans, animals and plants but also play crucial roles in the ecology of …

Understanding evolutionary and functional relationships of RNA polymerases in plant and fungal viruses through structural modeling and divergence date estimations

J Gracy, M Ghafari, G Labesse, D Fargette, E Hébrard - bioRxiv, 2024 - biorxiv.org
RNA-dependent RNA polymerases (RdRps) are crucial for replication of RNA viruses and
serve as key marker genes for defining deep taxonomic ranks and for understanding viral …