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Recent advancement of piperidine moiety in treatment of cancer-A review
Piperidine is an important pharmacophore, a privileged scaffold and an excellent
heterocyclic system in the field of drug discovery which provides numerous opportunities in …
heterocyclic system in the field of drug discovery which provides numerous opportunities in …
Alkaloids from apocynaceae: origin, pharmacotherapeutic properties, and structure-activity studies
A Dey, A Mukherjee, M Chaudhury - Studies in natural products chemistry, 2017 - Elsevier
Alkaloids are a diverse group of naturally occurring secondary compounds derived from
amino acids or the process of transamination. Some synthetic compounds with similar …
amino acids or the process of transamination. Some synthetic compounds with similar …
Palladium‐catalyzed regioselective aromatic extension of internal alkynes through a norbornene‐controlled reaction sequence
A regioselective aromatic π‐extension reaction of internal alkynes is reported. The proposed
method employs three easily available components, namely aryl halides, 2 …
method employs three easily available components, namely aryl halides, 2 …
Iodide-Dependent Selective Dehydroaromatization Affording Maleimide-Fused 9, 10-Phenanthrenes and Their Analogues
S Wang, Z Chen, S Chen, W Shao, Y Chen… - Organic …, 2023 - ACS Publications
A novel and selective synthesis of polycyclic fused maleimides from easily available raw
materials under metal-free conditions is presented. This cascade protocol involves self …
materials under metal-free conditions is presented. This cascade protocol involves self …
Design, synthesis, and biological activity of sulfonamide analogues of antofine and cryptopleurine as potent and orally active antitumor agents
Due to their profound antiproliferative activity and unique mode of action,
phenanthroindolizidine and phenanthroquinolizidine alkaloids, represented by antofine and …
phenanthroindolizidine and phenanthroquinolizidine alkaloids, represented by antofine and …
Pd-Catalyzed Alkene-Relayed Intermolecular C–H Alkylation Using Aryl Halide Substrates
S Yang, Y Zhang - Organic Letters, 2022 - ACS Publications
Alkene-relayed C–H activation represents a novel strategy for functionalizing C–H bonds
selectively. We developed a Pd-catalyzed annulation reaction of 2-iodobiphenyls with …
selectively. We developed a Pd-catalyzed annulation reaction of 2-iodobiphenyls with …
Design, synthesis, and antiviral evaluation of phenanthrene-based tylophorine derivatives as potential antiviral agents
K Wang, Y Hu, Y Liu, N Mi, Z Fan, Y Liu… - Journal of agricultural …, 2010 - ACS Publications
A series of C9-substituted phenanthrene-based tylophorine derivatives (PBTs) were
designed, synthesized, and first evaluated for their antiviral activities against tobacco mosaic …
designed, synthesized, and first evaluated for their antiviral activities against tobacco mosaic …
Multi-omics strategy reveals that Cordyceps sinensis ameliorates sepsis-associated acute kidney injury via reprogramming of mitochondrial energy metabolism and …
L Chen, T Yang, J Wu, G Cheng, M Zhao… - Acta Materia …, 2024 - scienceopen.com
Cordyceps sinensis (CS) has been widely used as a dietary supplement or traditional
medicine for the prevention, treatment, and prognostication of various diseases, because of …
medicine for the prevention, treatment, and prognostication of various diseases, because of …
Alkaloids as anticancer agents: a review of Chinese patents in recent 5 years
Background: In recent years, many novel alkaloids with anticancer activity have been found
in China, and some of them are promising for develo** as anticancer agents. Objective …
in China, and some of them are promising for develo** as anticancer agents. Objective …
Directed Metalation–Suzuki–Miyaura Cross-Coupling Strategies: Regioselective Synthesis of Hydroxylated 1-Methyl-phenanthrenes
KB Jørgensen, T Rantanen, T Dörfler… - The Journal of Organic …, 2015 - ACS Publications
A general, efficient, and regioselective synthesis of a series of hydroxylated 1-
methylphenanthrenes 9 by a combined directed ortho metalation (DoM)–Suzuki–Miyaura …
methylphenanthrenes 9 by a combined directed ortho metalation (DoM)–Suzuki–Miyaura …