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Progesterone and estrogen signaling in the endometrium: what goes wrong in endometriosis?
In the healthy endometrium, progesterone and estrogen signaling coordinate in a tightly
regulated, dynamic interplay to drive a normal menstrual cycle and promote an embryo …
regulated, dynamic interplay to drive a normal menstrual cycle and promote an embryo …
Progesterone action in endometrial cancer, endometriosis, uterine fibroids, and breast cancer
Progesterone receptor (PR) mediates the actions of the ovarian steroid progesterone, which
together with estradiol regulates gonadotropin secretion, prepares the endometrium for …
together with estradiol regulates gonadotropin secretion, prepares the endometrium for …
Physiological and molecular determinants of embryo implantation
Embryo implantation involves the intimate interaction between an implantation-competent
blastocyst and a receptive uterus, which occurs in a limited time period known as the …
blastocyst and a receptive uterus, which occurs in a limited time period known as the …
Uterine glands: developmental biology and functional roles in pregnancy
All mammalian uteri contain glands in the endometrium that develop only or primarily after
birth. Gland development or adenogenesis in the postnatal uterus is intrinsically regulated …
birth. Gland development or adenogenesis in the postnatal uterus is intrinsically regulated …
Organoid co-culture model of the human endometrium in a fully synthetic extracellular matrix enables the study of epithelial-stromal crosstalk
Background The human endometrium undergoes recurring cycles of growth, differentiation,
and breakdown in response to sex hormones. Dysregulation of epithelial-stromal …
and breakdown in response to sex hormones. Dysregulation of epithelial-stromal …
Estrogen receptor null mice: what have we learned and where will they lead us?
JF Couse, KS Korach - Endocrine reviews, 1999 - academic.oup.com
Elwood Jensen and Jack Gorski had spent 10 yr providing experimental evidence to support
the concept of an intracellular “receptor” protein for steroid hormones. Their combined work …
the concept of an intracellular “receptor” protein for steroid hormones. Their combined work …
Cyclical endometrial repair and regeneration
Uniquely among adult tissues, the human endometrium undergoes cyclical shedding, scar-
free repair and regeneration during a woman's reproductive life. Therefore, it presents an …
free repair and regeneration during a woman's reproductive life. Therefore, it presents an …
Endocrine regulation of menstruation
HN Jabbour, RW Kelly, HM Fraser… - Endocrine …, 2006 - academic.oup.com
In women, endometrial morphology and function undergo characteristic changes every
menstrual cycle. These changes are crucial for perpetuation of the species and are …
menstrual cycle. These changes are crucial for perpetuation of the species and are …
The Science behind 25 Years of Ovarian Stimulation for in Vitro Fertilization
To allow selection of embryos for transfer after in vitro fertilization, ovarian stimulation is
usually carried out with exogenous gonadotropins. To compensate for changes induced by …
usually carried out with exogenous gonadotropins. To compensate for changes induced by …
Innate and adaptive immunity in female genital tract: cellular responses and interactions
The mucosal immune system in the female reproductive tract (FRT) has evolved to meet the
unique requirements of dealing with sexually transmitted bacterial and viral pathogens …
unique requirements of dealing with sexually transmitted bacterial and viral pathogens …