Arousal and consciousness in focal seizures

H Blumenfeld - Epilepsy Currents, 2021 - journals.sagepub.com
Impaired consciousness during seizures severely affects quality of life for people with
epilepsy but the mechanisms are just beginning to be understood. Consciousness is thought …

[HTML][HTML] Understanding focal seizures in adults: A comprehensive review

Y Ghulaxe, A Joshi, J Chavada, S Huse, B Kalbande… - Cureus, 2023 - ncbi.nlm.nih.gov
Focal or partial seizures are a common neurological disorder affecting adults. This review
aims to provide an in-depth understanding of focal seizures in adults, including their …

[HTML][HTML] Slow and fast cortical cholinergic arousal is reduced in a mouse model of focal seizures with impaired consciousness

LA Sieu, S Singla, J Liu, X Zheng, A Sharafeldin… - Cell Reports, 2024 - cell.com
Patients with focal temporal lobe seizures often experience loss of consciousness
associated with cortical slow waves, like those in deep sleep. Previous work in rat models …

Cortical low‐frequency power correlates with behavioral impairment in animal model of focal limbic seizures

A Gummadavelli, R Martin, D Goshay, LA Sieu, J Xu… - …, 2021 - Wiley Online Library
Objective Impairment in consciousness is a debilitating symptom during and after seizures;
however, its mechanism remains unclear. Limbic seizures have been shown to spread to …