Nanocarrier drug delivery systems: characterization, limitations, future perspectives and implementation of artificial intelligence
There has been an increasing demand for the development of nanocarriers targeting
multiple diseases with a broad range of properties. Due to their tiny size, giant surface area …
multiple diseases with a broad range of properties. Due to their tiny size, giant surface area …
Proteomics of human biological fluids for biomarker discoveries: technical advances and recent applications
L Dayon, O Cominetti, M Affolter - Expert review of proteomics, 2022 - Taylor & Francis
Introduction Biological fluids are routine samples for diagnostic testing and monitoring.
Blood samples are typically measured because of their moderate invasive collection and …
Blood samples are typically measured because of their moderate invasive collection and …
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches
JA Welsh, DCI Goberdhan, L O'Driscoll… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …
origin and change the functions and phenotypes of other cells. These features indicate …
[HTML][HTML] Functional characterization of the dural sinuses as a neuroimmune interface
Despite the established dogma of central nervous system (CNS) immune privilege,
neuroimmune interactions play an active role in diverse neurological disorders. However …
neuroimmune interactions play an active role in diverse neurological disorders. However …
Nanoformulation properties, characterization, and behavior in complex biological matrices: Challenges and opportunities for brain-targeted drug delivery applications …
V Agrahari, PA Burnouf, T Burnouf… - Advanced Drug Delivery …, 2019 - Elsevier
Nanocarriers (synthetic/cell-based have attracted enormous interest for various therapeutic
indications, including neurodegenerative disorders. A broader understanding of the impact …
indications, including neurodegenerative disorders. A broader understanding of the impact …
Integrated analysis of the cerebrospinal fluid peptidome and proteome
A Zougman, B Pilch, A Podtelejnikov… - Journal of proteome …, 2008 - ACS Publications
Cerebrospinal fluid (CSF) is the only body fluid in direct contact with the brain and thus is a
potential source of biomarkers. Furthermore, CSF serves as a medium of endocrine …
potential source of biomarkers. Furthermore, CSF serves as a medium of endocrine …
Metabolic adaptation of acute lymphoblastic leukemia to the central nervous system microenvironment depends on stearoyl-CoA desaturase
AM Savino, SI Fernandes, O Olivares, A Zemlyansky… - Nature cancer, 2020 - nature.com
Metabolic reprogramming is a key hallmark of cancer, but less is known about metabolic
plasticity of the same tumor at different sites. Here, we investigated the metabolic adaptation …
plasticity of the same tumor at different sites. Here, we investigated the metabolic adaptation …
Common data elements for traumatic brain injury: recommendations from the biospecimens and biomarkers working group
GT Manley, R Diaz-Arrastia, M Brophy, D Engel… - Archives of physical …, 2010 - Elsevier
Manley GT, Diaz-Arrastia R, Brophy M, Engel D, Goodman C, Gwinn K, Veenstra TD, Ling G,
Ottens AK, Tortella F, Hayes RL. Common data elements for traumatic brain injury …
Ottens AK, Tortella F, Hayes RL. Common data elements for traumatic brain injury …
Cerebrospinal fluid levels of alpha-synuclein measured using a poly-glutamic acid-modified gold nanoparticle-doped disposable neuro-biosensor system
MNS Karaboğa, MK Sezgintürk - Analyst, 2019 - pubs.rsc.org
Alpha-synuclein (SYN) is a prominent key protein in Parkinson-type dementia. Measurement
of the amount of this protein found in the cerebrospinal fluid (CSF) using precise techniques …
of the amount of this protein found in the cerebrospinal fluid (CSF) using precise techniques …
Deep dive on the proteome of human cerebrospinal fluid: a valuable data resource for biomarker discovery and missing protein identification
Cerebrospinal fluid (CSF) is a body fluid of choice for biomarker studies of brain disorders
but remains relatively under-studied compared with other biological fluids such as plasma …
but remains relatively under-studied compared with other biological fluids such as plasma …