In the past decade, membraneless assemblies known as biomolecular condensates have
been reported to play key roles in many cellular functions by compartmentalizing specific …

The development of cancer is intimately associated with genetic abnormalities that target
proteins with intrinsically disordered regions (IDRs). In human haematological malignancies …

Prostate cancer (PCa) affects millions of men globally. Due to advances in understanding
genomic landscapes and biological functions, the treatment of PCa continues to improve …

Sex exerts a profound impact on cancer incidence, spectrum and outcomes, yet the
molecular and genetic bases of such sex differences are ill-defined and presumptively …

Transcription factors (TFs) represent key biological players in diseases including cancer,
autoimmunity, diabetes and cardiovascular disease. However, outside nuclear receptors …