[HTML][HTML] Disease networks and their contribution to disease understanding: A review of their evolution, techniques and data sources

EPG Del Valle, GL García, LP Santamaría… - Journal of biomedical …, 2019 - Elsevier
Over a decade ago, a new discipline called network medicine emerged as an approach to
understand human diseases from a network theory point-of-view. Disease networks proved …

Protein–protein interaction network: an emerging tool for understanding fish disease in aquaculture

K Waiho, N Afiqah‐Aleng, MTM Iryani… - Reviews in …, 2021 - Wiley Online Library
Protein–protein interactions (PPIs) play integral roles in a wide range of biological
processes that regulate the overall growth, development, physiology and disease in living …

ACE2 interaction networks in COVID-19: a physiological framework for prediction of outcome in patients with cardiovascular risk factors

Z Wicik, C Eyileten, D Jakubik, SN Simões… - Journal of clinical …, 2020 - mdpi.com
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
(coronavirus disease 2019; COVID-19) is associated with adverse outcomes in patients with …

[HTML][HTML] Protein–protein interaction network analysis reveals several diseases highly associated with polycystic ovarian syndrome

B Ramly, N Afiqah-Aleng… - International journal of …, 2019 - mdpi.com
Based on clinical observations, women with polycystic ovarian syndrome (PCOS) are prone
to develo** several other diseases, such as metabolic and cardiovascular diseases …

Gene set enrichment analysis of alpha-glucosidase inhibitors from Ficus benghalensis

P Khanal, BM Patil - Asian Pacific Journal of Tropical Biomedicine, 2019 - journals.lww.com
Objective: To identify alpha-glucosidase inhibitors from Ficus benghalensis and analyze
gene set enrichment of regulated protein molecules. Methods: The phytoconstituents of …

A fingerprint of plasma proteome alteration after local tissue damage induced by Bothrops leucurus snake venom in mice

J dos Santos Cavalcante, CAS de Almeida… - Journal of …, 2022 - Elsevier
Bothrops spp. is responsible for about 70% of snakebites in Brazil, causing a diverse and
complex pathophysiological condition. Bothrops leucurus is the main species of medical …

[HTML][HTML] Multi-level biological network analysis and drug repurposing based on leukocyte transcriptomics in severe COVID-19: in silico systems biology to precision …

P Sagulkoo, H Chuntakaruk, T Rungrotmongkol… - Journal of personalized …, 2022 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic causes many morbidity and mortality
cases. Despite several developed vaccines and antiviral therapies, some patients …

Prediction of Human-Plasmodium vivax Protein Associations From Heterogeneous Network Structures Based on Machine-Learning Approach

A Suratanee, T Buaboocha… - … and Biology Insights, 2021 - journals.sagepub.com
Malaria caused by Plasmodium vivax can lead to severe morbidity and death. In addition,
resistance has been reported to existing drugs in treating this malaria. Therefore, the …

Genome wide prediction, map** and development of genomic resources of mastitis associated genes in water buffalo

S Jaiswal, J Jagannadham, J Kumari… - Frontiers in veterinary …, 2021 - frontiersin.org
Water buffalo (Bubalus bubalis) are an important animal resource that contributes milk,
meat, leather, dairy products, and power for plowing and transport. However, mastitis, a …

Heterogeneous network propagation with forward similarity integration to enhance drug–target association prediction

P Tangmanussukum, T Kawichai, A Suratanee… - PeerJ Computer …, 2022 - peerj.com
Identification of drug–target interaction (DTI) is a crucial step to reduce time and cost in the
drug discovery and development process. Since various biological data are publicly …