Diabetic retinopathy (DR) is a diabetic complication which affects retinal function and results
in severe loss of vision and relevant retinal diseases. Retinal vascular dysfunction caused …

Heat shock protein 27 (HSP27) is traditionally viewed as an intracellular chaperone protein
with anti-apoptotic properties. However, recent data indicate that a number of heat shock …

The significance of oxidative stress in the development of chronic neurodegenerative
diseases of the retina has become increasingly apparent in recent years. Reactive oxygen …

The retinal pigment epithelium (RPE) performs a range of necessary functions within the
neural layers of the retina and helps ensure vision. The regulation of pro-oxidative and …

Heat shock proteins (HSPs) are a family of proteins that are expressed by cells in reply to
stressors. The changes in concentration of HSPs could be utilized as a bio-indicator of …

Oxidative stress plays key roles in the pathogenesis of retinal diseases, such as diabetic
retinopathy. Reactive oxygen species (ROS) are increased in the retina in diabetes and the …

Inflammation and oxidative stress play pivotal roles in pathogenesis of many diseases
including cancer, type 2 diabetes, cardiovascular disease, atherosclerosis, neurological …

Heat shock proteins (HSPs) are a large family of proteins highly conserved throughout
evolution because of their unique cytoprotective properties. Besides assisting protein …

Abstract microRNA (miRNA) play critical roles in the pathological processes of diabetic
retinopathy, including inflammatory responses, insulin signaling, and angiogenesis. In …

The present work was done to elucidate whether hemichannels of a cell line derived from
endothelial cells are affected by pro-inflammatory conditions (high glucose and IL-1β/TNF-α) …