The evolution of SARS-CoV-2

PV Markov, M Ghafari, M Beer, K Lythgoe… - Nature Reviews …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
deaths and substantial morbidity worldwide. Intense scientific effort to understand the …

The disease severity and clinical outcomes of the SARS-CoV-2 variants of concern

L Lin, Y Liu, X Tang, D He - Frontiers in public health, 2021 - frontiersin.org
With the continuation of the pandemic, many severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) variants have appeared around the world. Owing to a possible risk of …

[HTML][HTML] Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B. 1.617. 2) compared with alpha (B. 1.1. 7) variants of concern: a cohort …

KA Twohig, T Nyberg, A Zaidi, S Thelwall… - The Lancet Infectious …, 2022 - thelancet.com
Summary Background The SARS-CoV-2 delta (B. 1.617. 2) variant was first detected in
England in March, 2021. It has since rapidly become the predominant lineage, owing to high …

Evaluation of the relative virulence of novel SARS-CoV-2 variants: a retrospective cohort study in Ontario, Canada

DN Fisman, AR Tuite - Cmaj, 2021 - cmaj.ca
Background: Between February and June 2021, the initial wild-type strains of SARS-CoV-2
were supplanted in Ontario, Canada, by new variants of concern (VOCs), first those with the …

Antigenic cartography of SARS-CoV-2 reveals that Omicron BA. 1 and BA. 2 are antigenically distinct

AZ Mykytyn, M Rissmann, A Kok, ME Rosu… - Science …, 2022 - science.org
The emergence and rapid spread of SARS-CoV-2 variants may affect vaccine efficacy
substantially. The Omicron variant termed BA. 2, which differs substantially from BA. 1 based …

The global epidemic of the SARS-CoV-2 delta variant, key spike mutations and immune escape

D Tian, Y Sun, J Zhou, Q Ye - Frontiers in immunology, 2021 - frontiersin.org
During the COVID-19 pandemic, SARS-CoV-2 variants have emerged and spread
worldwide. The Delta (B. 1.617. 2) variant was first reported in India in October 2020 and …

Immunogenicity and safety of the CoronaVac inactivated vaccine in patients with autoimmune rheumatic diseases: a phase 4 trial

AC Medeiros-Ribeiro, NE Aikawa, CGS Saad… - Nature medicine, 2021 - nature.com
CoronaVac, an inactivated SARS-CoV-2 vaccine, has been approved for emergency use in
several countries. However, its immunogenicity in immunocompromised individuals has not …

Two years into the COVID-19 pandemic: lessons learned

SJR da Silva, JCF do Nascimento… - ACS infectious …, 2022 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
and virulent human-infecting coronavirus that emerged in late December 2019 in Wuhan …

Remdesivir for the treatment of COVID‐19

F Grundeis, K Ansems, K Dahms… - The Cochrane …, 2023 - pmc.ncbi.nlm.nih.gov
Background Remdesivir is an antiviral medicine approved for the treatment of mild‐to‐
moderate coronavirus disease 2019 (COVID‐19). This led to widespread implementation …

SARS-CoV-2 spreads through cell-to-cell transmission

C Zeng, JP Evans, T King, YM Zheng, EM Oltz… - Proceedings of the …, 2022 - pnas.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
coronavirus responsible for the global COVID-19 pandemic. Herein, we provide evidence …