Ionic liquids: new forms of active pharmaceutical ingredients with unique, tunable properties

JL Shamshina, RD Rogers - Chemical Reviews, 2023 - ACS Publications
This Review aims to summarize advances over the last 15 years in the development of
active pharmaceutical ingredient ionic liquids (API-ILs), which make up a prospective game …

Biological activity of ionic liquids and their application in pharmaceutics and medicine

KS Egorova, EG Gordeev, VP Ananikov - Chemical reviews, 2017 - ACS Publications
Ionic liquids are remarkable chemical compounds, which find applications in many areas of
modern science. Because of their highly tunable nature and exceptional properties, ionic …

The role of ionic liquids in the pharmaceutical field: An overview of relevant applications

SN Pedro, CS R. Freire, AJD Silvestre… - International journal of …, 2020 - mdpi.com
Solubility, bioavailability, permeation, polymorphism, and stability concerns associated to
solid-state pharmaceuticals demand for effective solutions. To overcome some of these …

Application of deep eutectic solvents in the extraction and separation of target compounds from various samples

B Tang, H Zhang, KH Row - Journal of separation science, 2015 - Wiley Online Library
Deep eutectic solvents, as a new type of eco‐friendly solvent, have attracted increasing
attention in chemistry for the extraction and separation of target compounds from various …

Deep-eutectic solvents playing multiple roles in the synthesis of polymers and related materials

D Carriazo, MC Serrano, MC Gutiérrez… - Chemical Society …, 2012 - pubs.rsc.org
The aim of this review is to provide an exposition of some of the most recent applications of
deep-eutectic solvents (DESs) in the synthesis of polymers and related materials. We …

Ionic liquids for energy, materials, and medicine

M Smiglak, JM Pringle, X Lu, L Han, S Zhang… - Chemical …, 2014 - pubs.rsc.org
As highlighted by the recent ChemComm web themed issue on ionic liquids, this field
continues to develop beyond the concept of interesting new solvents for application in the …

Ionic liquids in pharmaceutical applications

IM Marrucho, LC Branco… - Annual review of chemical …, 2014 - annualreviews.org
In the past several years, ionic liquids (ILs) have been at the cutting edge of the most
promising science and technology. ILs not only have found applications in classical areas of …

Ionic liquids as active pharmaceutical ingredients

R Ferraz, LC Branco, C Prudencio… - …, 2011 - Wiley Online Library
Ionic liquids (ILs) are ionic compounds that possess a melting temperature below 100° C.
Their physical and chemical properties are attractive for various applications. Several …

Ionic liquid/water mixtures: from hostility to conciliation

Y Kohno, H Ohno - Chemical Communications, 2012 - pubs.rsc.org
Water was originally inimical to ionic liquids (ILs) especially in the analysis of their detailed
properties. Various data on the properties of ILs indicate that there are two ways to design …

Ionic liquids in drug delivery

JL Shamshina, PS Barber… - Expert opinion on drug …, 2013 - Taylor & Francis
Introduction: To overcome potential problems with solid-state APIs, such as polymorphism,
solubility and bioavailability, pure liquid salt (ionic liquid) forms of active pharmaceutical …