Strategies for Improving Transdermal Administration: New Approaches to Controlled Drug Release

O Dumitriu Buzia, AM Păduraru, CS Stefan, M Dinu… - Pharmaceutics, 2023 - mdpi.com
In this work, we aim to address several strategies to improve transdermal drug delivery, such
as iontophoresis, sonophoresis, electroporation and micron. We also propose a review of …

Ionic liquid-based formulation approaches for enhanced transmucosal drug delivery

O Khan, R Bhawale, R Vasave, NK Mehra - Drug Discovery Today, 2024 - Elsevier
Highlights•ILs, a potential approach for improving physico-chemical and biological
properties of APIs.•Mucus membranes serves as a barrier for drug delivery.•Choline-based …

[HTML][HTML] Strategies for Improving Transdermal Administration: New Approaches to Controlled Drug Release

OD Buzia, AM Păduraru, CS Stefan, M Dinu… - …, 2023 - ncbi.nlm.nih.gov
In this work, we aim to address several strategies to improve transdermal drug delivery, such
as iontophoresis, sonophoresis, electroporation and micron. We also propose a review of …

Green solvents tailored nanostructures of block copolymers and their potential applications in drug delivery

A Kumar, M Saha, R Vishwakarma, K Behera… - Journal of Molecular …, 2024 - Elsevier
In the past decades, deep eutectic solvents (DESs) and ionic liquids (ILs) have garnered
significant interest in various disciplines of the chemical, physical and biological sciences as …

Ionic Liquid-Mediated Transdermal Delivery of Organogel Containing Cyclosporine A for the Effective Treatment of Psoriasis

D Datta, SP Bandi, VVK Venuganti - ACS omega, 2024 - ACS Publications
The dermal delivery of peptide therapeutics that are of high molecular weight is a challenge.
Cyclosporine A (CsA) is a cyclic undecapeptide with poor aqueous solubility and high …

[PDF][PDF] Permeation enhancement and advanced strategies: A comprehensive review of improved topical drug delivery

BA Patel - International Research Journal of Modernization in …, 2024 - researchgate.net
Transdermal drug delivery offers a promising alternative to conventional routes, with benefits
like painless administration and avoidance of first-pass metabolism. However, the skin's …

Mechanisms of Biological Effects of Ionic Liquids: From Single Cells to Multicellular Organisms

KS Egorova, AV Kibardin, AV Posvyatenko… - Chemical …, 2024 - ACS Publications
The review presents a detailed discussion of the evolving field studying interactions
between ionic liquids (ILs) and biological systems. Originating from molten salt electrolytes …

Advances of ionic liquid-based nanohybrids for biomedical applications

LY Li, YR Gao, R Xue, Y Shu, JH Wang… - Journal of Materials …, 2023 - pubs.rsc.org
Ionic liquids (ILs) are composed of asymmetric cationic and anionic moieties and are used
as green solvents. Their non-toxic nature, favorable biocompatibility and adjustable structure …

[HTML][HTML] Mixed Micellar Gel of Poloxamer Mixture for Improved Solubilization of Poorly Water-Soluble Ibuprofen and Use as Thermosensitive In Situ Gel

N Hirun, P Kraisit, S Santhan - Pharmaceutics, 2024 - mdpi.com
The aqueous solution of binary mixtures of amphiphilic copolymers is a potential platform for
fabricating mixed polymeric micelles for pharmaceutical applications, particularly in …

Utilizing ionic liquids as eco-friendly and sustainable carriers for delivering nucleic acids: A review on the revolutionary advancement in nano delivery systems

E Mirhadi, P Kesharwani, SK Jha, S Karav… - International Journal of …, 2024 - Elsevier
Ionic liquids (ILs) are an extremely versatile class of chemicals. It has been shown that they
can effectively pass through many biological barriers in the human body to deliver …