Diabetes mellitus has become a serious and chronic metabolic disorder that results from a
complex interaction of genetic and environmental factors, principally characterized by …

Diabetes mellitus most commonly occurs after the neonatal period and results from complex
interactions between both environmental and incompletely penetrant genetic factors …

KATP channels are integral to the functions of many cells and tissues. The use of
electrophysiological methods has allowed for a detailed characterization of KATP channels …

“The first step in wisdom is to know the things themselves; this notion consists in having a
true idea of the objects; objects are distinguished and known by classifying them …

This review focuses on the human pancreatic islet—including its structure, cell composition,
development, function, and dysfunction. After providing a historical timeline of key …

Cantú syndrome (CS), first described in 1982, is caused by pathogenic variants in ABCC9
and KCNJ8, which encode the regulatory and pore forming subunits of ATP‐sensitive …

Neonatal diabetes (NDM) is a rare monogenic disorder that presents as hyperglycemia
during the first six months of life. The link between early-life gut microbiota dysbiosis and …

Diabetes mellitus is a metabolic and chronic disorder, which is very common all over the
world. Many genetic and nongenetic factors are involved in the development of type 2 …

Pancreatic islets secrete insulin from β cells and glucagon from α cells, and dysregulated
secretion of these hormones is a central component of diabetes. Thus, an improved …

Neonatal diabetes mellitus (NDM) is noted as a genetic, heterogeneous, and rare disease in
infants. NDM occurs due to a single-gene mutation in neonates. A common source for …