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Antimicrobial peptides: An alternative to traditional antibiotics
S Ji, F An, T Zhang, M Lou, J Guo, K Liu, Y Zhu… - European Journal of …, 2024 - Elsevier
As antibiotic-resistant bacteria and genes continue to emerge, the identification of effective
alternatives to traditional antibiotics has become a pressing issue. Antimicrobial peptides …
alternatives to traditional antibiotics has become a pressing issue. Antimicrobial peptides …
Antimicrobial peptides: an update on classifications and databases
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …
indispensable component of host defenses. They consist of predominantly short cationic …
Identification of potent antimicrobial peptides via a machine-learning pipeline that mines the entire space of peptide sequences
J Huang, Y Xu, Y Xue, Y Huang, X Li, X Chen… - Nature Biomedical …, 2023 - nature.com
Systematically identifying functional peptides is difficult owing to the vast combinatorial
space of peptide sequences. Here we report a machine-learning pipeline that mines the …
space of peptide sequences. Here we report a machine-learning pipeline that mines the …
CAMPR4: a database of natural and synthetic antimicrobial peptides
There has been an exponential increase in the design of synthetic antimicrobial peptides
(AMPs) for its use as novel antibiotics. Synthetic AMPs are substantially enriched in residues …
(AMPs) for its use as novel antibiotics. Synthetic AMPs are substantially enriched in residues …
sAMPpred-GAT: prediction of antimicrobial peptide by graph attention network and predicted peptide structure
K Yan, H Lv, Y Guo, W Peng, B Liu - Bioinformatics, 2023 - academic.oup.com
Abstract Motivation Antimicrobial peptides (AMPs) are essential components of therapeutic
peptides for innate immunity. Researchers have developed several computational methods …
peptides for innate immunity. Researchers have developed several computational methods …
DBAASP v3: database of antimicrobial/cytotoxic activity and structure of peptides as a resource for development of new therapeutics
Abstract The Database of Antimicrobial Activity and Structure of Peptides (DBAASP) is an
open-access, comprehensive database containing information on amino acid sequences …
open-access, comprehensive database containing information on amino acid sequences …
Cell-free biosynthesis combined with deep learning accelerates de novo-development of antimicrobial peptides
Bioactive peptides are key molecules in health and medicine. Deep learning holds a big
promise for the discovery and design of bioactive peptides. Yet, suitable experimental …
promise for the discovery and design of bioactive peptides. Yet, suitable experimental …
ToxinPred 3.0: An improved method for predicting the toxicity of peptides
Toxicity emerges as a prominent challenge in the design of therapeutic peptides, causing
the failure of numerous peptides during clinical trials. In 2013, our group developed …
the failure of numerous peptides during clinical trials. In 2013, our group developed …
APD3: the antimicrobial peptide database as a tool for research and education
G Wang, X Li, Z Wang - Nucleic acids research, 2016 - academic.oup.com
The antimicrobial peptide database (APD, http://aps. unmc. edu/AP/) is an original database
initially online in 2003. The APD2 (2009 version) has been regularly updated and further …
initially online in 2003. The APD2 (2009 version) has been regularly updated and further …
Antioxidant and antimicrobial peptides derived from food proteins
Recently, the demand for food proteins in the market has increased due to a rise in
degenerative illnesses that are associated with the excessive production of free radicals and …
degenerative illnesses that are associated with the excessive production of free radicals and …