The term inflammatory bowel disease (IBD) refers principally to two major categories of
chronic relapsing inflammatory intestinal disorders: Crohn's disease (CD) and ulcerative …

Opioid Tolerance in Critical Illness | New England Journal of Medicine Skip to main content The
New England Journal of Medicine homepage Advanced Search SEARCH The New England …

Members of the heterotrimeric guanine nucleotide–binding protein (G protein)–coupled
receptor (GPCR) family play key roles in many physiological functions and are extensively …

Increasing concern about the risks and limited evidence supporting the therapeutic benefit of
long-term opioid therapy for chronic noncancer pain are leading prescribers to consider …

There is increasing evidence that brain− gut interactions are altered during development of
inflammatory bowel diseases (IBDs). Understanding the relationship between the …

In Brief The management of acute perioperative pain in patients on chronic buprenorphine
as opioid maintenance therapy is a complex process. We describe pain management …

Prevention of Opioid Overdose This review explains harm-reduction strategies for three
groups of patients: those who have not received previous opioid therapy, those receiving …

Importance Expanding Medicaid eligibility could affect prescriptions of buprenorphine with
naloxone, an established treatment for opioid use disorder, and opioid pain relievers …

Buprenorphine possesses many unique attributes that make it a practical agent for adults
and adolescents with opioid use disorder (OUD) and/or acute or chronic pain. Sublingual …

Background Policy evaluations and health system interventions often utilize International
Classification of Diseases (ICD) codes of opioid use, dependence, and abuse to identify …