Measurably recombining malaria parasites
F Camponovo, CO Buckee, AR Taylor - Trends in parasitology, 2023 - cell.com
Genomic epidemiology has guided research and policy for various viral pathogens and
there has been a parallel effort towards using genomic epidemiology to combat diseases …
there has been a parallel effort towards using genomic epidemiology to combat diseases …
Applying next-generation sequencing to track falciparum malaria in sub-Saharan Africa
Next-generation sequencing (NGS) technologies are increasingly being used to address a
diverse range of biological and epidemiological questions. The current understanding of …
diverse range of biological and epidemiological questions. The current understanding of …
SNP barcodes provide higher resolution than microsatellite markers to measure Plasmodium vivax population genetics
Background Genomic surveillance of malaria parasite populations has the potential to
inform control strategies and to monitor the impact of interventions. Barcodes comprising …
inform control strategies and to monitor the impact of interventions. Barcodes comprising …
Malaria molecular surveillance in the Peruvian Amazon with a novel highly multiplexed Plasmodium falciparum AmpliSeq assay
Molecular surveillance for malaria has great potential to support national malaria control
programs (NMCPs). To bridge the gap between research and implementation, several …
programs (NMCPs). To bridge the gap between research and implementation, several …
Molecular approaches to determine the multiplicity of Plasmodium infections
Multiplicity of infection (MOI), also termed complexity of infection (COI), is defined as the
number of genetically distinct parasite strains co-infecting a single host, which is an …
number of genetically distinct parasite strains co-infecting a single host, which is an …
R H: a genetic metric for measuring intrahost Plasmodium falciparum relatedness and distinguishing cotransmission from superinfection
Multiple-strain (polygenomic) infections are a ubiquitous feature of Plasmodium falciparum
parasite population genetics. Under simple assumptions of superinfection, polygenomic …
parasite population genetics. Under simple assumptions of superinfection, polygenomic …
The Diversity, Multiplicity of Infection and Population Structure of P. falciparum Parasites Circulating in Asymptomatic Carriers Living in High and Low Malaria …
Z Abukari, R Okonu, SB Nyarko, AC Lo, CC Dieng… - Genes, 2019 - mdpi.com
Background: Diversity in Plasmodium falciparum poses a major threat to malaria control and
elimination interventions. This study utilized 12 polymorphic microsatellite (MS) markers and …
elimination interventions. This study utilized 12 polymorphic microsatellite (MS) markers and …
Global analysis of Plasmodium falciparum histidine-rich protein-2 (pfhrp2) and pfhrp3 gene deletions using whole-genome sequencing data and meta-analysis
Many rapid diagnostic tests (RDT) used on suspected malaria cases are based on the
detection of the protein encoded by the Plasmodium falciparum histidine-rich protein-2 …
detection of the protein encoded by the Plasmodium falciparum histidine-rich protein-2 …
Multiplicity and molecular epidemiology of Plasmodium vivax and Plasmodium falciparum infections in East Africa
Background Parasite genetic diversity and multiplicity of infection (MOI) affect clinical
outcomes, response to drug treatment and naturally-acquired or vaccine-induced immunity …
outcomes, response to drug treatment and naturally-acquired or vaccine-induced immunity …
Hypnozoite dynamics for Plasmodium vivax malaria: the epidemiological effects of radical cure
Malaria is a mosquito-borne disease with a devastating global impact. Plasmodium vivax is
a major cause of human malaria beyond sub-Saharan Africa. Relapsing infections, driven by …
a major cause of human malaria beyond sub-Saharan Africa. Relapsing infections, driven by …