Cerebral small vessel disease

J Litak, M Mazurek, B Kulesza, P Szmygin… - International journal of …, 2020 - mdpi.com
Cerebral small vessel disease (CSVD) represents a cluster of various vascular disorders
with different pathological backgrounds. The advanced vasculature net of cerebral vessels …

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the …

P Lewczuk, P Riederer, SE O'bryant… - The world journal of …, 2018 - Taylor & Francis
In the 12 years since the publication of the first Consensus Paper of the WFSBP on
biomarkers of neurodegenerative dementias, enormous advancement has taken place in …

Lymphatic drainage system of the brain: a novel target for intervention of neurological diseases

BL Sun, L Wang, T Yang, J Sun, L Mao, M Yang… - Progress in …, 2018 - Elsevier
The belief that the vertebrate brain functions normally without classical lymphatic drainage
vessels has been held for many decades. On the contrary, new findings show that functional …

The increasing impact of cerebral amyloid angiopathy: essential new insights for clinical practice

G Banerjee, R Carare, C Cordonnier… - Journal of Neurology …, 2017 - jnnp.bmj.com
Cerebral amyloid angiopathy (CAA) has never been more relevant. The last 5 years have
seen a rapid increase in publications and research in the field, with the development of new …

White matter hyperintensities and CSF Alzheimer disease biomarkers in preclinical Alzheimer disease

A Soldan, C Pettigrew, Y Zhu, MC Wang, A Moghekar… - Neurology, 2020 - AAN Enterprises
Objective Recent studies suggest that white matter hyperintensities (WMH) on MRI, which
primarily reflect small vessel cerebrovascular disease, may play a role in the evolution of …

[HTML][HTML] Predicting Fazekas scores from automatic segmentations of white matter signal abnormalities

N Cedres, D Ferreira, A Machado, S Shams… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Different measurements of white matter signal abnormalities (WMSA) are often used across
studies, which hinders combination of WMSA data from different cohorts. We investigated …

[HTML][HTML] Dysfunction of the blood-brain barrier in cerebral microbleeds: from bedside to bench

H Wang, C Zhang, Y Qiu, A Chen, Y Li, B Hu - Aging and disease, 2021 - ncbi.nlm.nih.gov
Cerebral microbleeds (CMBs) are a disorder of cerebral microvessels that are characterized
as small (< 10 mm), hypointense, round or ovoid lesions seen on T2*-weighted gradient …

Cerebral small vessel disease and the risk of Alzheimer's disease: a systematic review

Y Liu, N Braidy, A Poljak, DKY Chan, P Sachdev - Ageing research reviews, 2018 - Elsevier
Background Cerebral small vessel disease (CSVD) comprises a variety of disorders
affecting small arteries and microvessels of the brain, manifesting as white matter …

[HTML][HTML] Cerebral amyloid burden is associated with white matter hyperintensity location in specific posterior white matter regions

NA Weaver, T Doeven, F Barkhof, JM Biesbroek… - Neurobiology of …, 2019 - Elsevier
White matter hyperintensities (WMHs) are a common manifestation of cerebral small vessel
disease. WMHs are also frequently observed in patients with familial and sporadic …

CSF amyloid is a consistent predictor of white matter hyperintensities across the disease course from aging to Alzheimer's disease

P Walsh, CH Sudre, CM Fiford, NS Ryan, T Lashley… - Neurobiology of …, 2020 - Elsevier
This study investigated the relationship between white matter hyperintensities (WMH) and
cerebrospinal fluid (CSF) Alzheimer's disease (AD) biomarkers. Subjects included 180 …