The hippocampus and prefrontal cortex (PFC) have long been known to play a central role
in various behavioral and cognitive functions. More recently, electrophysiological and …

Autism spectrum disorders (ASD) are characterized by two seemingly unrelated symptom
domains—deficits in social interactions and restrictive, repetitive patterns of behavioral …

The successful planning and execution of adaptive behaviors in mammals may require long-
range coordination of neural networks throughout cerebral cortex. The neuronal …

While the dopamine hypothesis has dominated schizophrenia research for several decades,
more recent studies have highlighted the role of fast synaptic transmitters and their receptors …

Although sensitizing processes occur earlier, schizophrenia is diagnosed in young
adulthood, which suggests that it might involve a pathological transition during late brain …

Defined genetic models based on human pluripotent stem cells have opened new avenues
for understanding disease mechanisms and drug screening. Many of these models assume …

Objective: Brain oscillations play a pivotal role in synchronizing responses of local and
global ensembles of neurons. Patients with schizophrenia exhibit impairments in oscillatory …

In the central nervous system (CNS), myelin sheaths around axons are formed by glial cells
named oligodendrocytes (OLs). In turn, OLs are generated by oligodendrocyte precursor …

Synaptic plasticity alters the strength of information flow between presynaptic and
postsynaptic neurons and thus modifies the likelihood that action potentials in a presynaptic …

Alterations in neocortical GABAergic interneurons (INs) have been affiliated with
neuropsychiatric diseases, including schizophrenia (SZ). Significant progress has been …