The task of develo** CPG documents covers not only integration of the most recent
research, but also the creation of educational tools and implementation programmes for the …

Fluoropyrimidines such as 5-fluorouracil (5-FU) form the foundation of a wide variety of
chemotherapy regimens. 5-FU is in fact the third most commonly used chemotherapeutic …

In 2008, the Guidelines for diagnosis and treatment of patients with vasospastic angina
(coronary spastic angina) 1 were developed by the Japanese Circulation Society, and the …

Antineoplastic drugs can be associated with several side effects, including cardiovascular
toxicity (CTX). Biochemical studies have identified multiple mechanisms of CTX …

Opinion statement Fluoropyrimidine (FP) is used to treat a wide range of cancers; however, it
is associated with drug-induced vascular toxicity, as well as angina pectoris and coronary …

Significance: Antineoplastic therapies have significantly improved the prognosis of oncology
patients. However, these treatments can bring to a higher incidence of side-effects, including …

Cancer patients experienced an increased risk of cardiotoxicity during fluoropyrimidine-
based chemotherapy (5-fluorouracil or capecitabine). We searched PubMed, PsycINFO, IPA …

Abstract Fluoropyrimidines (5-fluorouracil and capecitabine) are antimetabolite drugs,
widely used for the treatment of a variety of cancers, both in adjuvant and in metastatic …

Abstract Fluoropyrimidines—5-fluorouracil (5-FU) and capecitabine—have been implicated
as cardiotoxic chemotherapy agents. This rare, albeit potentially serious toxicity has been …

Novel therapeutic options have significantly improved survival and long-term outcomes in
many cancer entities. Unfortunately, this improvement in outcome is often accompanied by …