The incidence of chronic osteomyelitis is increasing because of the prevalence of
predisposing conditions such as diabetes mellitus and peripheral vascular disease. The …

This review article summarizes the recent advances in pathogenic mechanisms and novel
therapeutic strategies for osteomyelitis, covering both periprosthetic joint infections and …

Background Traumatic amputation leads to disability and imposes a heavy health burden.
This study aims to explore the current status and temporal trends of the global burden of …

Background: The epidemiology of osteomyelitis in the United States is largely unknown. The
purpose of this study was to determine long-term secular trends in the incidence of …

Objective: To examine the association between antibiotic timing and deep infection of type III
open tibia fractures. Design: Retrospective prognostic study. Setting: Level 1 Trauma Center …

Purpose Like many classification systems, the purpose of the Gustilo-Anderson schema is to
provide a prognostic framework that guides treatment and facilitates communication among …

Importance Open fractures of the lower limb occur when a broken bone penetrates the skin.
There can be major complications from these fractures, which can be life-changing …

Background: Existing guidelines recommend emergency surgical debridement of open
fractures within six hours after injury. The aim of this study was to systematically review the …

Purpose The purpose of this study was to identify risk factors for the development of infection
after open fracture fixation. Methods A comprehensive search in all scientific literature of the …

Background: Surgical site infection is one of the most common complications following ankle
fracture surgery. These infections are associated with substantial morbidity and lead to …