New insights and potential therapeutic targeting of CB2 cannabinoid receptors in CNS disorders
The endocannabinoid system (ECS) is ubiquitous in most human tissues, and involved in
the regulation of mental health. Consequently, its dysregulation is associated with …
the regulation of mental health. Consequently, its dysregulation is associated with …
Cannabinoid treatments in epilepsy and seizure disorders
Cannabis has been used to treat convulsions and other disorders since ancient times. In the
last few decades, preclinical animal studies and clinical investigations have established the …
last few decades, preclinical animal studies and clinical investigations have established the …
Potential role of cannabinoid type 2 receptors in neuropsychiatric and neurodegenerative disorders
The endocannabinoid system (ECS) is composed of the two canonical receptor subtypes;
type-1 cannabinoid (CB1R) and type 2 receptor (CB2R), endocannabinoids (eCBs) and …
type-1 cannabinoid (CB1R) and type 2 receptor (CB2R), endocannabinoids (eCBs) and …
Pharmacokinetic and tissue distribution study of eight volatile constituents in rats orally administrated with the essential oil of Artemisiae argyi Folium by GC–MS/MS
MZ Hou, LL Chen, C Chang, JF Zan, SM Du - Journal of Chromatography B, 2021 - Elsevier
Artemisia argyi is commonly used as a remedy for gynecological and respiratory disease in
traditional Chinese medicine. The essential oil is considered as the major active ingredients …
traditional Chinese medicine. The essential oil is considered as the major active ingredients …
[HTML][HTML] On the application of 3d metals for C–H activation toward bioactive compounds: The key step for the synthesis of silver bullets
RL Carvalho, AS de Miranda… - Beilstein Journal of …, 2021 - beilstein-journals.org
Several valuable biologically active molecules can be obtained through C–H activation
processes. However, the use of expensive and not readily accessible catalysts complicates …
processes. However, the use of expensive and not readily accessible catalysts complicates …
Cannabidiol and beta-caryophyllene in combination: a therapeutic functional interaction
H Blanton, L Yin, J Duong, K Benamar - International Journal of …, 2022 - mdpi.com
Cannabis contains over 500 distinct compounds, which include cannabinoids, terpenoids,
and flavonoids. However, very few of these compounds have been studied for their …
and flavonoids. However, very few of these compounds have been studied for their …
The CB2 Receptor as a Novel Therapeutic Target for Epilepsy Treatment
X Ji, Y Zeng, J Wu - International Journal of Molecular Sciences, 2021 - mdpi.com
Epilepsy is characterized by repeated spontaneous bursts of neuronal hyperactivity and
high synchronization in the central nervous system. It seriously affects the quality of life of …
high synchronization in the central nervous system. It seriously affects the quality of life of …
β-caryophyllene cationic nanoemulsion for intranasal delivery and treatment of epilepsy: development and in vivo evaluation of anticonvulsant activity
C Nogueira, E Lemos-Senna, E da Silva Vieira… - Journal of Nanoparticle …, 2023 - Springer
Intranasal delivery systems have been proposed as alternative routes for drug delivery to the
brain, primarily for treating diseases that affect the central nervous system. β-Caryophyllene …
brain, primarily for treating diseases that affect the central nervous system. β-Caryophyllene …
Bridging the gap: The endocannabinoid system as a functional fulcrum for benzodiazepines in a novel frontier of anxiety pharmacotherapy
While benzodiazepines have been a mainstay of the pharmacotherapy of anxiety disorders,
their short-term efficacy and risk of abuse have driven the exploration of alternative treatment …
their short-term efficacy and risk of abuse have driven the exploration of alternative treatment …
Plant based food bioactives: A boon or bane for neurological disorders
N Choudhary, D Tewari, SF Nabavi… - Critical Reviews in …, 2024 - Taylor & Francis
Neurological disorders are the foremost occurring diseases across the globe resulting in
progressive dysfunction, loss of neuronal structure ultimately cell death. Therefore, attention …
progressive dysfunction, loss of neuronal structure ultimately cell death. Therefore, attention …