Diagnostic, prognostic, and mechanistic biomarkers of diabetes mellitus-associated cognitive decline
Cognitive dysfunctions such as mild cognitive impairment (MCI), Alzheimer's disease (AD),
and other forms of dementia are recognized as common comorbidities of type 2 diabetes …
and other forms of dementia are recognized as common comorbidities of type 2 diabetes …
Understanding multifactorial brain changes in type 2 diabetes: a biomarker perspective
People with type 2 diabetes are at an increased risk of cognitive impairment and dementia
(including Alzheimer's disease), as well as subtle forms of cognitive dysfunction. Current …
(including Alzheimer's disease), as well as subtle forms of cognitive dysfunction. Current …
Classification and deep-learning–based prediction of Alzheimer disease subtypes by using genomic data
D Shigemizu, S Akiyama, M Suganuma… - Translational …, 2023 - nature.com
Late-onset Alzheimer's disease (LOAD) is the most common multifactorial
neurodegenerative disease among elderly people. LOAD is heterogeneous, and the …
neurodegenerative disease among elderly people. LOAD is heterogeneous, and the …
Aerobic exercise training improves cerebral blood flow and executive function: a randomized, controlled cross-over trial in sedentary older men
Background Physical activity may attenuate age-related cognitive decline by improving
cerebrovascular function. The aim of this study was therefore to investigate effects of aerobic …
cerebrovascular function. The aim of this study was therefore to investigate effects of aerobic …
The association of regional cerebral blood flow and glucose metabolism in normative ageing and insulin resistance
Rising rates of insulin resistance and an ageing population are set to exact an increasing toll
on individuals and society. Here we examine the contribution of age and insulin resistance …
on individuals and society. Here we examine the contribution of age and insulin resistance …
Brain metabolism alterations in type 2 diabetes: what did we learn from diet-induced diabetes models?
AM Garcia-Serrano, JMN Duarte - Frontiers in neuroscience, 2020 - frontiersin.org
Type 2 diabetes (T2D) is a metabolic disease with impact on brain function through
mechanisms that include glucose toxicity, vascular damage and blood–brain barrier (BBB) …
mechanisms that include glucose toxicity, vascular damage and blood–brain barrier (BBB) …
Effects of food supplementation on cognitive function, cerebral blood flow, and nutritional status in young children at risk of undernutrition: randomized controlled trial
SB Roberts, MA Franceschini, RE Silver, SF Taylor… - bmj, 2020 - bmj.com
Objective To assess the effects of food supplementation on improving working memory and
additional measures including cerebral blood flow in children at risk of undernutrition …
additional measures including cerebral blood flow in children at risk of undernutrition …
It's about time: the circadian network as time-keeper for cognitive functioning, locomotor activity and mental health
A variety of organisms including mammals have evolved a 24h, self-sustained timekee**
machinery known as the circadian clock (biological clock), which enables to anticipate …
machinery known as the circadian clock (biological clock), which enables to anticipate …
[HTML][HTML] Emerging links between cerebral blood flow regulation and cognitive decline: A role for brain microvascular pericytes
TY You, Q Dong, M Cui - Aging and Disease, 2023 - ncbi.nlm.nih.gov
Cognitive impairment associated with vascular etiology has been of considerable interest in
the development of dementia. Recent studies have started to uncover cerebral blood flow …
the development of dementia. Recent studies have started to uncover cerebral blood flow …
[HTML][HTML] Impairment of neurovascular coupling in the hippocampus due to decreased nitric oxide bioavailability supports early cognitive dysfunction in type 2 diabetic …
Numerous epidemiological and preclinical studies have established a strong correlation
between type 2 diabetes (T2DM) and cognitive impairment and T2DM is now established as …
between type 2 diabetes (T2DM) and cognitive impairment and T2DM is now established as …