Chitosan derivatives and their application in biomedicine

W Wang, Q Meng, Q Li, J Liu, M Zhou, Z **… - International journal of …, 2020 - mdpi.com
Chitosan is a product of the deacetylation of chitin, which is widely found in nature. Chitosan
is insoluble in water and most organic solvents, which seriously limits both its application …

A global review on short peptides: frontiers and perspectives

V Apostolopoulos, J Bojarska, TT Chai, S Elnagdy… - Molecules, 2021 - mdpi.com
Peptides are fragments of proteins that carry out biological functions. They act as signaling
entities via all domains of life and interfere with protein-protein interactions, which are …

Chitosan-based colloidal polyelectrolyte complexes for drug delivery: a review

D Wu, L Zhu, Y Li, X Zhang, S Xu, G Yang… - Carbohydrate polymers, 2020 - Elsevier
Polyelectrolyte complexes (PECs) as safe drug delivery carriers, are spontaneously formed
by mixing the oppositely charged polyelectrolyte solutions in water without using organic …

Immunostimulatory effect of chitosan and quaternary chitosan: A review of potential vaccine adjuvants

X Li, R **ng, C Xu, S Liu, Y Qin, K Li, H Yu, P Li - Carbohydrate polymers, 2021 - Elsevier
Vaccines have always been the most effective preventive treatment. Advancements in the
field of vaccine is inseparable from adjuvants. Adjuvants are substances added to vaccines …

Developments in vaccine adjuvants

FZ Firdaus, M Skwarczynski, I Toth - Vaccine Design: Methods and …, 2022 - Springer
Vaccines, including subunit, recombinant, and conjugate vaccines, require the use of an
immunostimulator/adjuvant for maximum efficacy. Adjuvants not only enhance the strength …

[HTML][HTML] Chitosan-based nanomaterial as immune adjuvant and delivery carrier for vaccines

X Gong, Y Gao, J Shu, C Zhang, K Zhao - Vaccines, 2022 - mdpi.com
With the support of modern biotechnology, vaccine technology continues to iterate. The
safety and efficacy of vaccines are some of the most important areas of development in the …

[HTML][HTML] Biomedical applications of quaternized chitosan

K Pathak, SK Misra, A Sehgal, S Singh, S Bungau… - Polymers, 2021 - mdpi.com
The natural polymer chitosan is the second most abundant biopolymer on earth after chitin
and has been extensively explored for preparation of versatile drug delivery systems. The …

Advancements in prophylactic and therapeutic nanovaccines

P Bhardwaj, E Bhatia, S Sharma, N Ahamad… - Acta Biomaterialia, 2020 - Elsevier
Vaccines activate suitable immune responses to fight against diseases but can possess
limitations such as compromised efficacy and immunogenic responses, poor stability, and …

Recent advances on chitosan as an adjuvant for vaccine delivery

I Dmour, N Islam - International Journal of Biological Macromolecules, 2022 - Elsevier
Chitosan (CS) is a natural polymer derived from chitin that has wide applications in drugs,
vaccines, and antigen delivery. The distinctive mucoadhesive, biocompatibility …

Untangling mucosal drug delivery: engineering, designing, and testing nanoparticles to overcome the mucus barrier

J Watchorn, AJ Clasky, G Prakash… - ACS biomaterials …, 2022 - ACS Publications
Mucus is a complex viscoelastic gel and acts as a barrier covering much of the soft tissue in
the human body. High vascularization and accessibility have motivated drug delivery to …