Oxidative stress results from a cell or tissue failing to detoxify the free radicals that are
produced during metabolic activity. Diabetes is characterized by chronic hyperglycemia that …

Oxidative stress has been repetitively shown to be a hallmark of many diseases linked with
metabolic or vascular disorders. Therefore diabetes represents an ideal candidate for …

The term “metabolic syndrome”(MetS) refers to a combination of diabetes, high blood
pressure, and obesity. The origin of MetS includes a combination of multiple factors, such as …

Paracetamol (acetaminophen, PCM) is widely used as an over-the-counter analgesic and
antipyretic drug. Intake of a large dose of PCM may result in severe hepatic necrosis …

Diabetic neuropathy (DN) represents the main cause of morbidity and mortality among
diabetic patients. Clinical data support the conclusion that the severity of DN is related to the …

Metabolic syndrome (MetS) is highly associated with a modern lifestyle. The prevalence of
MetS has reached epidemic proportion and is still rising. The main cause of MetS and finally …

The metabolic syndrome (MS) recognized as a major cause of type 2 diabetes and
cardiovascular diseases, has become one of the major public health challenges worldwide …

Macroautophagy is a degradation/recycling system ubiquitous in eukariotic cells, which
generates nutrients during fasting under the control of amino acids and hormones, and …

Abstract δ-ALA-D is a metalloenzyme that has 3 vicinal thiol/thiolate groups that coordinate
with Zn (ii). The proximity between the sulfhydryl groups renders δ-ALA-D extremely …

Diet is a key component for development and longevity of organisms. Here, the fruit fly was
used to evaluate the detrimental effects caused by consumption of high-sucrose diets (HSD) …