The causes and consequences of trained immunity in myeloid cells

G Bhargavi, S Subbian - Frontiers in immunology, 2024 - frontiersin.org
Conventionally, immunity in humans has been classified as innate and adaptive, with the
concept that only the latter type has an immunological memory/recall response against …

Structure, functions, and implications of selected lipocalins in human disease

P Chandrasekaran, S Weiskirchen… - International Journal of …, 2024 - mdpi.com
The lipocalin proteins are a large family of small extracellular proteins that demonstrate
significant heterogeneity in sequence similarity and have highly conserved crystal …

The signaling pathways in obesity‐related complications

P Chandrasekaran… - Journal of Cell …, 2024 - Wiley Online Library
Obesity, a rapidly expanding epidemic worldwide, is known to exacerbate many medical
conditions, making it a significant factor in multiple diseases and their associated …

Network pharmacology combined with molecular docking and molecular dynamic simulation to reveal the potential mechanism of lentinan ameliorating …

Z Chu, L Zeng, F Yang, Z Hu, Y Luo, Y Zhou, Y Tang… - Food Bioscience, 2024 - Elsevier
Hyperlipidemia is closely related to multiple diseases and is characterized by abnormal
serum lipid profiles. The biological function of lentinan in mice and rats was studied, but the …

Perilipins: A family of five fat‐droplet storing proteins that play a significant role in fat homeostasis

P Chandrasekaran, S Weiskirchen… - Journal of Cellular …, 2024 - Wiley Online Library
Lipid droplets are organelles with unique spherical structures. They consist of a hydrophobic
neutral lipid core that varies depending on the cell type and tissue. These droplets are …

Role of lipid metabolism in hepatocellular carcinoma

Y Cheng, J He, B Zuo, Y He - Discover Oncology, 2024 - Springer
Hepatocellular carcinoma (HCC), an aggressive malignancy with a dismal prognosis, poses
a significant public health challenge. Recent research has highlighted the crucial role of lipid …

Regulation of cGAS–STING signalling and its diversity of cellular outcomes

Z Zhang, C Zhang - Nature Reviews Immunology, 2025 - nature.com
The cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) signalling
pathway, which recognizes both pathogen DNA and host-derived DNA, has emerged as a …

The cellular and molecular targets of natural products against metabolic disorders: a translational approach to reach the bedside

X Shen, H Yang, Y Yang, X Zhu, Q Sun - MedComm, 2024 - Wiley Online Library
Metabolic disorders, including obesity, dyslipidemia, diabetes, nonalcoholic fatty liver
disease, and metabolic syndrome, are characterized by insulin resistance, abnormalities in …

NAT10 promotes liver lipogenesis in mouse through N4-acetylcytidine modification of Srebf1 and Scap mRNA

Z Wang, X Wan, MA Khan, L Peng, X Sun, X Yi… - Lipids in Health and …, 2024 - Springer
Background Metabolic dysfunction associated steatotic liver disease (MASLD), closely
linked to excessive lipogenesis, induces chronic liver disease. MASLD often cause other …

Cardamom consumption may improve cardiovascular metabolic biomarkers in adults: A systematic review and meta-analysis of randomized controlled trials

X Zhang, C Wang, R Min, Q Zhou, Y Qi, J Fan - Nutrition Research, 2024 - Elsevier
The bioactive compounds in cardamom have been found to enhance cardiovascular health
by improving blood lipids and inflammation. We hypothesized that cardamom consumption …