The prefrontal cortex (PFC) has emerged as one of the regions most consistently impaired in
major depressive disorder (MDD). Although functional and structural PFC abnormalities …

Abstract Concepts of cognitive control (CC) and executive function (EF) are defined in terms
of their relationships with goal-directed behavior versus habits and controlled versus …

Humans require a plethora of higher cognitive skills to perform executive functions, such as
reasoning, planning, language and social interactions, which are regulated predominantly …

Obsessive-compulsive disorder is a severe and disabling psychiatric disorder that presents
several challenges for neuroscience. Recent advances in its genetic and developmental …

The roles of the hippocampus and prefrontal cortex (PFC) in memory processing—
individually or in concert—are a major topic of interest in memory research. These brain …

The brain is characterized by heterogeneous patterns of structural connections supporting
unparalleled feats of cognition and a wide range of behaviours. New non-invasive imaging …

A decade ago, we hypothesized that drug addiction can be viewed as a transition from
voluntary, recreational drug use to compulsive drug-seeking habits, neurally underpinned by …

Reversal learning paradigms are among the most widely used tests of cognitive flexibility
and have been used as assays, across species, for altered cognitive processes in a host of …

Introduction: Executive function (EF) skills emerge in infancy and typically become more
effective and efficient throughout childhood and adolescence and into early adulthood …

In many circumstances alternative courses of action and thoughts have to be inhibited to
allow the emergence of goal-directed behavior. However, this has not been the accepted …