The use of hadron beams, especially proton beams, in cancer radiotherapy has expanded
rapidly in the past two decades. To fully realize the advantages of hadron therapy over …

Proton radiography and tomography have long promised benefit for proton therapy. Their
first suggestion was in the early 1960s and the first published proton radiographs and CT …

Because of the vast availability of data, there has been an additional focus on the health
industry and an increasing number of studies that aim to leverage the data to improve …

Ion computed tomography (iCT) represents a potential replacement for x-ray CT (xCT) in ion
therapy treatment planning to reduce range uncertainties, inherent in the semi-empirical …

Purpose: To evaluate the spatial resolution of proton CT using both a prototype proton CT
scanner and Monte Carlo simulations. Methods: A custom cylindrical edge phantom …

In practical applications of computed tomography (CT) imaging, due to the risk of high
radiation dose imposed on the patients, it is desired that high quality CT images can be …

Purpose: Accurately predicting the range of radiotherapy ions in vivo is important for the
precise delivery of dose in particle therapy. Range uncertainty is currently the single largest …

This is a review paper on some of the physics, modeling, and iterative algorithms in proton
computed tomography (pCT) image reconstruction. The primary challenge in pCT image …

Proton computed tomography (CT) has been demonstrated as a promising image modality
in particle therapy planning. It can reduce errors in particle range calculations and …

Algebraic iterative methods are routinely used for solving the ill-posed sparse linear systems
arising in tomographic image reconstruction. Here we consider the algebraic reconstruction …