BACKGROUND For people with diabetes mellitus to achieve optimal glycaemic control,
motivation to perform self-management is important. The research team wanted to determine …

BACKGROUND Warfarin is effective for stroke prevention in atrial fibrillation (AF), but
anticoagulation is underused in clinical care. The risk of venous thromboembolic disease …

The allocation of healthcare resources among competing priorities requires an assessment
of the expected costs and health effects of investing resources in the activities and of the …

In a previous paper we introduced a distribution-based method for Global Sensitivity
Analysis (GSA), called PAWN, which uses cumulative distribution functions of model outputs …

This book is an expository introduction to the methodology of sensitivity analysis of model
output. It is primarily intended for investigators, students and researchers that are familiar …

Probabilistic sensitivity analysis (PSA) demonstrates the parameter uncertainty in a decision
problem. The technique involves sampling parameters from their respective distributions …

Background Gestational diabetes mellitus (GDM) is associated with a higher risk of
important adverse outcomes. Practice varies and the best strategy for identifying and treating …

Value of information (VoI) is a decision-theoretic approach to estimating the expected
benefits from collecting further information of different kinds, in scientific problems based on …

Objectives Health technology assessment (HTA) uses evidence appraisal and synthesis
with economic evaluation to inform adoption decisions. Standard HTA processes sometimes …

Measures of sensitivity and uncertainty have become an integral part of risk analysis. Many
such measures have a conditional probabilistic structure, for which a straightforward Monte …