Major depression is one of the most prevalent and debilitating personal and public health
conditions worldwide. Less appreciated is that depression's tremendous burdens are not …

Objectives: To provide guidance for the management of mood disorders, based on scientific
evidence supplemented by expert clinical consensus and formulate recommendations to …

Catatonia is a psychomotor syndrome associated with several psychiatric and medical
conditions. Psychomotor signs range from stupor to agitation, and include pathognomonic …

Electroconvulsive therapy (ECT), which has been in use for 75 years, is an important
treatment for severe and treatment-resistant depression. Although it is acknowledged as the …

Objective Catatonia, a disorder of movement and mood, was described and named in 1874.
Other observers quickly made the same recognition. By the turn of the century, however …

Catatonia is a motor dysregulation syndrome among psychiatric asylum patients that was
delineated in 1874. The syndrome was so well characterized that within a few years its …

Approximately half of the people who suffer a major depressive episode for the first time
experience recurrences, while the other half do not. Among the initially depressed, however …

Suicide is a leading cause of death among psychiatric patients, and a leading cause of
death from all causes in people younger than 30 years. The rapid relief of severe …

Conclusions Melancholia is a lifetime diagnosis, typically with recurrent episodes (5, 6, 13,
14). Within the present classification it is frequently seen in severely ill patients with major …

This article reviews 3 current theories of electroconvulsive therapy (ECT). One theory points
to generalized seizures as essential for the therapeutic efficacy of ECT. Another theory …