Clinical neurology and epidemiology of the major neurodegenerative diseases
MG Erkkinen, MO Kim… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Neurodegenerative diseases are a common cause of morbidity and cognitive impairment in
older adults. Most clinicians who care for the elderly are not trained to diagnose these …
older adults. Most clinicians who care for the elderly are not trained to diagnose these …
Alzheimer disease: epidemiology, diagnostic criteria, risk factors and biomarkers
The global prevalence of dementia is as high as 24 million, and has been predicted to
quadruple by the year 2050. In the US alone, Alzheimer disease (AD)–the most frequent …
quadruple by the year 2050. In the US alone, Alzheimer disease (AD)–the most frequent …
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound‐B
This report describes the first human study of a novel amyloid‐imaging positron emission
tomography (PET) tracer, termed Pittsburgh Compound‐B (PIB), in 16 patients with …
tomography (PET) tracer, termed Pittsburgh Compound‐B (PIB), in 16 patients with …
Alzheimer's disease
Alzheimer's disease is the most common cause of dementia. Research advances have
enabled detailed understanding of the molecular pathogenesis of the hallmarks of the …
enabled detailed understanding of the molecular pathogenesis of the hallmarks of the …
Epidemiology of Alzheimer disease
The global prevalence of dementia is estimated to be as high as 24 million, and is predicted
to double every 20 years through to 2040, leading to a costly burden of disease. Alzheimer …
to double every 20 years through to 2040, leading to a costly burden of disease. Alzheimer …
Imaging the evolution and pathophysiology of Alzheimer disease
W Jagust - Nature Reviews Neuroscience, 2018 - nature.com
Technologies for imaging the pathophysiology of Alzheimer disease (AD) now permit
studies of the relationships between the two major proteins deposited in this disease …
studies of the relationships between the two major proteins deposited in this disease …
Plasma phospholipids identify antecedent memory impairment in older adults
Alzheimer's disease causes a progressive dementia that currently affects over 35 million
individuals worldwide and is expected to affect 115 million by 2050 (ref. 1). There are no …
individuals worldwide and is expected to affect 115 million by 2050 (ref. 1). There are no …
EANM procedure guidelines for brain PET imaging using [18F]FDG, version 3
The present procedural guidelines summarize the current views of the EANM Neuro-
Imaging Committee (NIC). The purpose of these guidelines is to assist nuclear medicine …
Imaging Committee (NIC). The purpose of these guidelines is to assist nuclear medicine …
Alzheimer's disease
JL Cummings - New England Journal of Medicine, 2004 - Mass Medical Soc
The prevalence of Alzheimer's disease is predicted to reach 13.2 million cases in the United
States. This article considers current therapeutic approaches for Alzheimer's disease …
States. This article considers current therapeutic approaches for Alzheimer's disease …
Mitochondrial dysfunction in Alzheimer's disease: Role in pathogenesis and novel therapeutic opportunities
JM Perez Ortiz, RH Swerdlow - British journal of pharmacology, 2019 - Wiley Online Library
Dysfunction of cell bioenergetics is a common feature of neurodegenerative diseases, the
most common of which is Alzheimer's disease (AD). Disrupted energy utilization implicates …
most common of which is Alzheimer's disease (AD). Disrupted energy utilization implicates …