Mass spectrometry imaging (MSI) provides information about the spatial localization of
molecules in complex samples with high sensitivity and molecular selectivity. Although point …

Lipid imaging mass spectrometry (LIMS) allows for establishing the bidimensional
distribution of lipid species within a tissue section. One of the main advantages is the …

An increasing number of spatial multiomic workflows have recently been developed. Some
of these approaches have leveraged initial mass spectrometry imaging (MSI)-based spatial …

Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) can
provide spatially resolved molecular information about a sample. Recently, a postionization …

Spatial metabolomics using imaging mass spectrometry (MS) enables untargeted and label-
free metabolite map** in biological samples. Despite the range of available imaging MS …

Abstract Smith-Lemli-Opitz syndrome (SLOS) is a neurodevelopmental disorder caused by
genetic mutations in the DHCR7 gene, encoding the enzyme 3β-hydroxysterol-Δ 7 …

Tissues are a major focus of clinical research and histopathological diagnosis for a wide
range of diseases. Understanding the complex biomolecular manifestations of disease …

Abstract Smith-Lemli-Opitz syndrome (SLOS) is a metabolic disorder caused by genetic
mutations in the DHCR7 gene, leading to defective 3β-hydroxysterol-Δ 7-reductase …