Turnitin
降AI改写
早检测系统
早降重系统
Turnitin-UK版
万方检测-期刊版
维普编辑部版
Grammarly检测
Paperpass检测
checkpass检测
PaperYY检测
Inhibitory potential of nitrogen, oxygen and sulfur containing heterocyclic scaffolds against acetylcholinesterase and butyrylcholinesterase
Heterocycles are the key structures in organic chemistry owing to their immense applications
in the biological, chemical, and pharmaceutical fields. Heterocyclic compounds perform …
in the biological, chemical, and pharmaceutical fields. Heterocyclic compounds perform …
Bioactive aurones, indanones, and other hemiindigoid scaffolds: Medicinal chemistry and photopharmacology perspectives
LM Lazinski, G Royal, M Robin… - Journal of Medicinal …, 2022 - ACS Publications
Hemiindigoids comprise a range of natural and synthetic scaffolds that share the same
aromatic hydrocarbon backbone as well as promising biological and optical properties. The …
aromatic hydrocarbon backbone as well as promising biological and optical properties. The …
Novel inhibitors with sulfamethazine backbone: synthesis and biological study of multi-target cholinesterases and α-glucosidase inhibitors
The underlying cause of many metabolic diseases is abnormal changes in enzyme activity
in metabolism. Inhibition of metabolic enzymes such as cholinesterases (ChEs; …
in metabolism. Inhibition of metabolic enzymes such as cholinesterases (ChEs; …
Synthesis and evaluation of 1, 3, 5-triaryl-2-pyrazoline derivatives as potent dual inhibitors of urease and α-glucosidase together with their cytotoxic, molecular …
In the present work, a concise library of 1, 3, 5-triaryl-2-pyrazolines (2a–2q) was designed
and synthesized by employing a multistep strategy, and the newly synthesized compounds …
and synthesized by employing a multistep strategy, and the newly synthesized compounds …
DNA protection, molecular docking, antioxidant, antibacterial, enzyme inhibition, and enzyme kinetic studies for parietin, isolated from Xanthoria parietina (L.) Th. Fr.
Parietin was isolated from Xanthoria parietina (L.) Th. Fr.'(methanol: chloroform) extract,
using a silica column. 13 C NMR and 1H NMR were used to confirm the structure of the …
using a silica column. 13 C NMR and 1H NMR were used to confirm the structure of the …
Para-Substituted Thiosemicarbazones as Cholinesterase Inhibitors: Synthesis, In Vitro Biological Evaluation, and In Silico Study
The current research reports the synthesis of 14 para-substituted thiosemicarbazone
derivatives in good to excellent yields using standard procedures. Initially, 4 …
derivatives in good to excellent yields using standard procedures. Initially, 4 …
Synthesis and biological evaluation of substituted aurone derivatives as potential tyrosinase inhibitors: in vitro, kinetic, QSAR, docking and drug-likeness studies
Tyrosinase enzyme plays an essential role in melanin biosynthesis and enzymatic browning
of fruits and vegetables. To discover potent tyrosinase inhibitors, the present studies were …
of fruits and vegetables. To discover potent tyrosinase inhibitors, the present studies were …
Synthetic flavonoids as potential antiviral agents against SARS-CoV-2 main protease
The COVID-19 pandemic has claimed more than a million lives worldwide within a short
time span. Due to the unavailability of specific antiviral drugs or vaccine, the infections are …
time span. Due to the unavailability of specific antiviral drugs or vaccine, the infections are …
Structural derivatization strategies of natural phenols by semi-synthesis and total-synthesis
D Lin, S Jiang, A Zhang, T Wu, Y Qian… - Natural products and …, 2022 - Springer
Structural derivatization of natural products has been a continuing and irreplaceable source
of novel drug leads. Natural phenols are a broad category of natural products with wide …
of novel drug leads. Natural phenols are a broad category of natural products with wide …
2-Benzylidenebenzofuran-3 (2 H)-ones as a new class of alkaline phosphatase inhibitors: synthesis, SAR analysis, enzyme inhibitory kinetics and computational …
The excelling role of organic chemistry in the medicinal field continues to be one of the main
leads in the drug development process. Particularly, this industry requires organic chemists …
leads in the drug development process. Particularly, this industry requires organic chemists …