The emergence, genomic diversity and global spread of SARS-CoV-2

J Li, S Lai, GF Gao, W Shi - Nature, 2021 - nature.com
Since the first cases of COVID-19 were documented in Wuhan, China in 2019, the world has
witnessed a devastating global pandemic, with more than 238 million cases, nearly 5 million …

SARS-CoV-2 variants, spike mutations and immune escape

WT Harvey, AM Carabelli, B Jackson… - Nature reviews …, 2021 - nature.com
Although most mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) genome are expected to be either deleterious and swiftly purged or relatively …

[HTML][HTML] Antibody resistance of SARS-CoV-2 variants B. 1.351 and B. 1.1. 7

P Wang, MS Nair, L Liu, S Iketani, Y Luo, Y Guo… - Nature, 2021 - nature.com
The COVID-19 pandemic has had widespread effects across the globe, and its causative
agent, SARS-CoV-2, continues to spread. Effective interventions need to be developed to …

[HTML][HTML] Increased resistance of SARS-CoV-2 variant P. 1 to antibody neutralization

P Wang, RG Casner, MS Nair, M Wang, J Yu… - Cell host & …, 2021 - cell.com
The emergence of SARS-CoV-2 variants has raised concerns about altered sensitivity to
antibody-mediated immunity. The relative resistance of SARS-CoV-2 variants B. 1.1. 7 and …

[HTML][HTML] Resurgence of COVID-19 in Manaus, Brazil, despite high seroprevalence

EC Sabino, LF Buss, MPS Carvalho, CA Prete… - The Lancet, 2021 - thelancet.com
Resurgence of COVID-19 in Manaus, Brazil, despite high seroprevalence - The Lancet Skip to
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Evidence for increased breakthrough rates of SARS-CoV-2 variants of concern in BNT162b2-mRNA-vaccinated individuals

T Kustin, N Harel, U Finkel, S Perchik, S Harari… - Nature medicine, 2021 - nature.com
The BNT162b2 mRNA vaccine is highly effective against SARS-CoV-2. However,
apprehension exists that variants of concern (VOCs) may evade vaccine protection, due to …

A comprehensive review of the global efforts on COVID-19 vaccine development

Y Li, R Tenchov, J Smoot, C Liu, S Watkins… - ACS central …, 2021 - ACS Publications
A Comprehensive Review of the Global Efforts on COVID-19 Vaccine Development | ACS
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[HTML][HTML] SARS-CoV-2 variant B. 1.1. 7 is susceptible to neutralizing antibodies elicited by ancestral spike vaccines

X Shen, H Tang, C McDanal, K Wagh, W Fischer… - Cell host & …, 2021 - cell.com
All current vaccines for COVID-19 utilize ancestral SARS-CoV-2 spike with the goal of
generating protective neutralizing antibodies. The recent emergence and rapid spread of …

Genomic characterization of a novel SARS-CoV-2 lineage from Rio de Janeiro, Brazil

CM Voloch, R da Silva Francisco Jr… - Journal of …, 2021 - journals.asm.org
Almost simultaneously, several studies reported the emergence of novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) lineages characterized by distinct …

Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants

L Wang, T Zhou, Y Zhang, ES Yang, CA Schramm… - Science, 2021 - science.org
INTRODUCTION Worldwide appearance of severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) variants of concern (VOCs) with increased transmissibility and resistance to …