In silico methods and tools for drug discovery
In the past, conventional drug discovery strategies have been successfully employed to
develop new drugs, but the process from lead identification to clinical trials takes more than …
develop new drugs, but the process from lead identification to clinical trials takes more than …
In silico approaches to identify polyphenol compounds as α-glucosidase and α-amylase inhibitors against type-II diabetes
Type-II diabetes mellitus (T2DM) results from a combination of genetic and lifestyle factors,
and the prevalence of T2DM is increasing worldwide. Clinically, both α-glucosidase and α …
and the prevalence of T2DM is increasing worldwide. Clinically, both α-glucosidase and α …
Identification of phytochemical inhibitors against main protease of COVID-19 using molecular modeling approaches
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel corona virus that
causes corona virus disease 2019 (COVID-19). The COVID-19 rapidly spread across the …
causes corona virus disease 2019 (COVID-19). The COVID-19 rapidly spread across the …
Food as medicine: A possible preventive measure against coronavirus disease (COVID‐19)
F Yang, Y Zhang, A Tariq, X Jiang… - Phytotherapy …, 2020 - Wiley Online Library
The recent and ongoing outbreak of coronavirus disease (COVID‐19) is a huge global
challenge. The outbreak, which first occurred in Wuhan City, Hubei Province, China and …
challenge. The outbreak, which first occurred in Wuhan City, Hubei Province, China and …
[HTML][HTML] Molecular docking analysis of rutin reveals possible inhibition of SARS-CoV-2 vital proteins
Background and aim COVID-19 emerged by the end of 2019 in Wuhan, China. It spreaded
and became a public health emergency all over the world by mid of April 2020. Flavonoids …
and became a public health emergency all over the world by mid of April 2020. Flavonoids …
Molecular communication and nanonetwork for targeted drug delivery: A survey
Molecular communication (MC) and molecular network (MN) are communication paradigms
that use biochemical signaling to achieve information exchange among naturally and …
that use biochemical signaling to achieve information exchange among naturally and …
Systematic screening of pharmaceutical polymers for hot melt extrusion processing: A comprehensive review
Pharmaceutical research, whether industrial or academic, has attempted to adopt
approaches most efficient for the development of innovations. With the abundance of …
approaches most efficient for the development of innovations. With the abundance of …
Antioxidant, Cytotoxicity, Antimicrobial Activity, and In Silico Analysis of the Methanolic Leaf and Flower Extracts of Clitoria ternatea
MA Islam, SK Mondal, S Islam… - Biochemistry …, 2023 - Wiley Online Library
Infectious diseases pose a significant threat to human health worldwide. To address this
challenge, we conducted a comprehensive study on the leaf and flower extracts of Clitoria …
challenge, we conducted a comprehensive study on the leaf and flower extracts of Clitoria …
Antiemetic effects of sclareol, possibly through 5-HT3 and D2 receptor interaction pathways: in-vivo and in-silico studies
Background Emesis is a complex physiological phenomenon that serves as a defense
against numerous toxins, stressful situations, adverse medication responses, chemotherapy …
against numerous toxins, stressful situations, adverse medication responses, chemotherapy …
Computer-aided analysis of phytochemicals as potential dengue virus inhibitors based on molecular docking, ADMET and DFT studies
Methods: A total of 2750 phytochemicals from different medicinal plants were selected for
this study. These plants grow naturally in the climate of Pakistan and India and have been …
this study. These plants grow naturally in the climate of Pakistan and India and have been …