Giant virus biology and diversity in the era of genome-resolved metagenomics

F Schulz, C Abergel, T Woyke - Nature Reviews Microbiology, 2022 - nature.com
The discovery of giant viruses, with capsids as large as some bacteria, megabase-range
genomes and a variety of traits typically found only in cellular organisms, was one of the …

Biology and pathogenesis of Acanthamoeba

R Siddiqui, NA Khan - Parasites & vectors, 2012 - Springer
Acanthamoeba is a free-living protist pathogen, capable of causing a blinding keratitis and
fatal granulomatous encephalitis. The factors that contribute to Acanthamoeba infections …

Systematic evaluation of horizontal gene transfer between eukaryotes and viruses

NAT Irwin, AA Pittis, TA Richards, PJ Keeling - Nature microbiology, 2022 - nature.com
Gene exchange between viruses and their hosts acts as a key facilitator of horizontal gene
transfer and is hypothesized to be a major driver of evolutionary change. Our understanding …

Giant virus diversity and host interactions through global metagenomics

F Schulz, S Roux, D Paez-Espino, S Jungbluth… - Nature, 2020 - nature.com
Our current knowledge about nucleocytoplasmic large DNA viruses (NCLDVs) is largely
derived from viral isolates that are co-cultivated with protists and algae. Here we …

[HTML][HTML] The symbiotic origin of the eukaryotic cell

P López-García, D Moreira - Comptes …, 2023 - comptes-rendus.academie-sciences …
Résumé L'eucaryogenèse représente une transition évolutive majeure qui a conduit à
l'émergence de cellules complexes à partir d'ancêtres plus simples. Pendant plusieurs …

Acanthamoeba, an environmental phagocyte enhancing survival and transmission of human pathogens

B Rayamajhee, MDP Willcox, FL Henriquez… - Trends in …, 2022 - cell.com
The opportunistic protist Acanthamoeba, which interacts with other microbes such as
bacteria, fungi, and viruses, shows significant similarity in cellular and functional aspects to …

The rapidly expanding universe of giant viruses: Mimivirus, Pandoravirus, Pithovirus and Mollivirus

C Abergel, M Legendre… - FEMS microbiology …, 2015 - academic.oup.com
More than a century ago, the term 'virus' was introduced to describe infectious agents that
are invisible by light microscopy and capable of passing through sterilizing filters. In addition …

Evolution of the large nucleocytoplasmic DNA viruses of eukaryotes and convergent origins of viral gigantism

EV Koonin, N Yutin - Advances in Virus Research, 2019 - Elsevier
Abstract The Nucleocytoplasmic Large DNA Viruses (NCLDV) of eukaryotes (proposed
order “Megavirales”) comprise an expansive group of eukaryotic viruses that consists of the …

The virophage as a unique parasite of the giant mimivirus

B La Scola, C Desnues, I Pagnier, C Robert, L Barrassi… - Nature, 2008 - nature.com
Viruses are obligate parasites of Eukarya, Archaea and Bacteria. Acanthamoeba polyphaga
mimivirus (APMV) is the largest known virus; it grows only in amoeba and is visible under …

A phylogenomic data-driven exploration of viral origins and evolution

A Nasir, G Caetano-Anollés - Science advances, 2015 - science.org
The origin of viruses remains mysterious because of their diverse and patchy molecular and
functional makeup. Although numerous hypotheses have attempted to explain viral origins …