Pathogenesis of human cytomegalovirus in the immunocompromised host

P Griffiths, M Reeves - Nature Reviews Microbiology, 2021 - nature.com
Human cytomegalovirus (HCMV) is a herpesvirus that infects~ 60% of adults in developed
countries and more than 90% in develo** countries. Usually, it is controlled by a vigorous …

Antiviral drug resistance of human cytomegalovirus

NS Lurain, S Chou - Clinical microbiology reviews, 2010 - Am Soc Microbiol
The study of human cytomegalovirus (HCMV) antiviral drug resistance has enhanced
knowledge of the virological targets and the mechanisms of antiviral activity. The currently …

Quantitative temporal viromics: an approach to investigate host-pathogen interaction

MP Weekes, P Tomasec, EL Huttlin, CA Fielding… - Cell, 2014 - cell.com
A systematic quantitative analysis of temporal changes in host and viral proteins throughout
the course of a productive infection could provide dynamic insights into virus-host …

Topics in herpesvirus genomics and evolution

DJ McGeoch, FJ Rixon, AJ Davison - Virus research, 2006 - Elsevier
Herpesviruses comprise an abundant, widely distributed group of large DNA viruses of
humans and other vertebrates, and overall are among the most extensively studied large …

[HTML][HTML] Herpesvirus systematics

AJ Davison - Veterinary microbiology, 2010 - Elsevier
This paper is about the taxonomy and genomics of herpesviruses. Each theme is presented
as a digest of current information flanked by commentaries on past activities and future …

Cytomegalovirus: pathogen, paradigm, and puzzle

M Boeckh, AP Geballe - The Journal of clinical investigation, 2011 - Am Soc Clin Investig
Human cytomegalovirus (CMV), one of the eight herpesviruses that commonly infect
humans, is best known for its propensity to cause disease in immunocompromised patients …

Isolation of human monoclonal antibodies that potently neutralize human cytomegalovirus infection by targeting different epitopes on the gH/gL/UL128-131A complex

A Macagno, NL Bernasconi, F Vanzetta… - Journal of …, 2010 - Am Soc Microbiol
Human cytomegalovirus (HCMV) is a widely circulating pathogen that causes severe
disease in immunocompromised patients and infected fetuses. By immortalizing memory B …

Cloning and sequencing of a highly productive, endotheliotropic virus strain derived from human cytomegalovirus TB40/E

C Sinzger, G Hahn, M Digel… - Journal of general …, 2008 - microbiologyresearch.org
Human cytomegalovirus (HCMV) strain TB40/E, replicates efficiently, exhibits a broad cell
tropism and is widely used for infection of endothelial cells and monocyte-derived cells yet …

Human cytomegalovirus entry into epithelial and endothelial cells depends on genes UL128 to UL150 and occurs by endocytosis and low-pH fusion

BJ Ryckman, MA Jarvis, DD Drummond… - Journal of …, 2006 - Am Soc Microbiol
Human cytomegalovirus (HCMV) replication in epithelial and endothelial cells appears to be
important in virus spread, disease, and persistence. It has been difficult to study infection of …

Characterization of the human cytomegalovirus gH/gL/UL128-131 complex that mediates entry into epithelial and endothelial cells

BJ Ryckman, BL Rainish, MC Chase, JA Borton… - Journal of …, 2008 - Am Soc Microbiol
The entry of human cytomegalovirus (HCMV) into biologically relevant epithelial and
endothelial cells involves endocytosis followed by low-pH-dependent fusion. This entry …