The global burden of coeliac disease: opportunities and challenges

GK Makharia, P Singh, C Catassi, DS Sanders… - Nature Reviews …, 2022 - nature.com
Coeliac disease is a systemic disorder characterized by immune-mediated enteropathy,
which is caused by gluten ingestion in genetically susceptible individuals. The clinical …

The emerging role of the small intestinal microbiota in human health and disease

RAAA Ruigrok, RK Weersma, A Vich Vila - Gut microbes, 2023 - Taylor & Francis
The human gut microbiota continues to demonstrate its importance in human health and
disease, largely owing to the countless number of studies investigating the fecal microbiota …

A human autoimmune organoid model reveals IL-7 function in coeliac disease

AJM Santos, V van Unen, Z Lin, SM Chirieleison, N Ha… - Nature, 2024 - nature.com
In vitro models of autoimmunity are constrained by an inability to culture affected epithelium
alongside the complex tissue-resident immune microenvironment. Coeliac disease (CeD) is …

Causal association between celiac disease and inflammatory bowel disease: A two-sample bidirectional Mendelian randomization study

S Yuan, JH Kim, P Xu, Z Wang - Frontiers in Immunology, 2023 - frontiersin.org
Background An epidemiological link between celiac disease (CeD) and inflammatory bowel
disease (IBD) has been well established recently. In this study, Mendelian randomization …

The emerging roles of bacterial proteases in intestinal diseases

A Caminero, M Guzman, J Libertucci, AE Lomax - Gut Microbes, 2023 - Taylor & Francis
Proteases are an evolutionarily conserved family of enzymes that degrade peptide bonds
and have been implicated in several common gastrointestinal (GI) diseases. Although …

Society for the Study of Celiac Disease position statement on gaps and opportunities in coeliac disease

MI Pinto-Sanchez, JA Silvester, B Lebwohl… - Nature Reviews …, 2021 - nature.com
Progress has been made in understanding coeliac disease, a relatively frequent and
underappreciated immune-mediated condition that occurs in genetically predisposed …

Gut microbiota dysbiosis in systemic lupus erythematosus: novel insights into mechanisms and promising therapeutic strategies

Q Pan, F Guo, Y Huang, A Li, S Chen, J Chen… - Frontiers in …, 2021 - frontiersin.org
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that was traditionally
thought to be closely related to genetic and environmental risk factors. Although treatment …

New developments in celiac disease treatment

MV Machado - International journal of molecular sciences, 2023 - mdpi.com
Celiac disease (CD) is a common autoimmune disease affecting around 1% of the
population. It consists of an immune-mediated enteropathy, triggered by gluten exposure in …

Coeliac disease

C Catassi, EF Verdu, JC Bai, E Lionetti - The Lancet, 2022 - thelancet.com
Coeliac disease is an autoimmune disorder that primarily affects the small intestine, and is
caused by the ingestion of gluten in genetically susceptible individuals. Prevalence in the …

Adverse food reactions: physiological and ecological perspectives

LL Korn, VI Kutyavin, ND Bachtel… - Annual Review of …, 2024 - annualreviews.org
While food is essential for survival, it can also cause a variety of harmful effects, ranging from
intolerance to specific nutrients to celiac disease and food allergies. In addition to nutrients …