Computational neuroethology: a call to action
The brain is worthy of study because it is in charge of behavior. A flurry of recent technical
advances in measuring and quantifying naturalistic behaviors provide an important …
advances in measuring and quantifying naturalistic behaviors provide an important …
The connectome of an insect brain
Brains contain networks of interconnected neurons and so knowing the network architecture
is essential for understanding brain function. We therefore mapped the synaptic-resolution …
is essential for understanding brain function. We therefore mapped the synaptic-resolution …
[HTML][HTML] Progress and remaining challenges in high-throughput volume electron microscopy
Highlights•Breakthrough in automatic neuron reconstruction from VEM data will enable the
reconstruction of much larger data sets in the future.•Volume electron microscopy imaging …
reconstruction of much larger data sets in the future.•Volume electron microscopy imaging …
[HTML][HTML] A connectome of the Drosophila central complex reveals network motifs suitable for flexible navigation and context-dependent action selection
Flexible behaviors over long timescales are thought to engage recurrent neural networks in
deep brain regions, which are experimentally challenging to study. In insects, recurrent …
deep brain regions, which are experimentally challenging to study. In insects, recurrent …
Structure and function of a neocortical synapse
S Holler, G Köstinger, KAC Martin, GFP Schuhknecht… - Nature, 2021 - nature.com
In 1986, electron microscopy was used to reconstruct by hand the entire nervous system of a
roundworm, the nematode Caenorhabditis elegans. Since this landmark study, high …
roundworm, the nematode Caenorhabditis elegans. Since this landmark study, high …
A complete electron microscopy volume of the brain of adult Drosophila melanogaster
Drosophila melanogaster has a rich repertoire of innate and learned behaviors. Its 100,000-
neuron brain is a large but tractable target for comprehensive neural circuit map**. Only …
neuron brain is a large but tractable target for comprehensive neural circuit map**. Only …
The complete connectome of a learning and memory centre in an insect brain
Associating stimuli with positive or negative reinforcement is essential for survival, but a
complete wiring diagram of a higher-order circuit supporting associative memory has not …
complete wiring diagram of a higher-order circuit supporting associative memory has not …
Recurrent architecture for adaptive regulation of learning in the insect brain
Dopaminergic neurons (DANs) drive learning across the animal kingdom, but the upstream
circuits that regulate their activity and thereby learning remain poorly understood. We …
circuits that regulate their activity and thereby learning remain poorly understood. We …
Cholinergic neurons trigger epithelial Ca2+ currents to heal the gut
A fundamental and unresolved question in regenerative biology is how tissues return to
homeostasis after injury. Answering this question is essential for understanding the …
homeostasis after injury. Answering this question is essential for understanding the …
[HTML][HTML] A neuropeptidergic circuit gates selective escape behavior of Drosophila larvae
Animals display selective escape behaviors when faced with environmental threats.
Selection of the appropriate response by the underlying neuronal network is key to …
Selection of the appropriate response by the underlying neuronal network is key to …