Functional Annotation of Animal Genomes (FAANG): current achievements and roadmap

E Giuffra, CK Tuggle… - Annual review of animal …, 2019 - annualreviews.org
Functional annotation of genomes is a prerequisite for contemporary basic and applied
genomic research, yet farmed animal genomics is deficient in such annotation. To address …

Micronutrients and brain development

D Mattei, A Pietrobelli - Current nutrition reports, 2019 - Springer
Abstract Purpose of Review This review summarizes the most recent evidence regarding the
effects of micronutrients on brain development. Recent Findings Emerging evidence …

The oncopig cancer model: an innovative large animal translational oncology platform

KM Schachtschneider, RM Schwind, J Newson… - Frontiers in …, 2017 - frontiersin.org
Despite an improved understanding of cancer molecular biology, immune landscapes, and
advancements in cytotoxic, biologic, and immunologic anti-cancer therapeutics, cancer …

Ferroptosis induction in multiple myeloma cells triggers DNA methylation and histone modification changes associated with cellular senescence

E Logie, B Van Puyvelde, B Cuypers… - International journal of …, 2021 - mdpi.com
Disease relapse and therapy resistance remain key challenges in treating multiple
myeloma. Underlying (epi-) mutational events can promote myelomagenesis and contribute …

Epigenetics and neurodegeneration: role of early-life nutrition

R Gabbianelli, E Damiani - The Journal of nutritional biochemistry, 2018 - Elsevier
Neurodegeneration represents a global problem due to the progressive increase in the
aging population all over the world. The quality of life in aging and the cost for the health …

Early-life iron deficiency anemia programs the hippocampal epigenomic landscape

AK Barks, SX Liu, MK Georgieff, TC Hallstrom, PV Tran - Nutrients, 2021 - mdpi.com
Iron deficiency (ID) anemia is the foremost micronutrient deficiency worldwide, affecting
around 40% of pregnant women and young children. ID during the prenatal and early …

The impact of maternal and early life malnutrition on health: a diet-microbe perspective

AJ Forgie, KM Drall, SL Bourque, CJ Field… - BMC medicine, 2020 - Springer
Background Early-life malnutrition may have long-lasting effects on microbe-host
interactions that affect health and disease susceptibility later in life. Diet quality and quantity …

Nurturing development: how a mother's nutrition shapes offspring's brain through the gut

MI Ionescu, CDM Zahiu, A Vlad, F Galos… - Nutritional …, 2025 - Taylor & Francis
Pregnancy is a transformative period marked by profound physical and emotional changes,
with far-reaching consequences for both mother and child. Emerging research has …

Maternal mineral nutrition regulates fetal genomic programming in cattle: A review

M Anas, WJS Diniz, ACB Menezes, LP Reynolds… - Metabolites, 2023 - mdpi.com
Maternal mineral nutrition during the critical phases of fetal development may leave lifetime
impacts on the productivity of an individual. Most research within the developmental origins …

The molecular basis of p21-activated kinase-associated neurodevelopmental disorders: From genotype to phenotype

M Dobrigna, S Poëa-Guyon, V Rousseau… - Frontiers in …, 2023 - frontiersin.org
Although the identification of numerous genes involved in neurodevelopmental disorders
(NDDs) has reshaped our understanding of their etiology, there are still major obstacles in …