Functional Annotation of Animal Genomes (FAANG): current achievements and roadmap
Functional annotation of genomes is a prerequisite for contemporary basic and applied
genomic research, yet farmed animal genomics is deficient in such annotation. To address …
genomic research, yet farmed animal genomics is deficient in such annotation. To address …
Micronutrients and brain development
D Mattei, A Pietrobelli - Current nutrition reports, 2019 - Springer
Abstract Purpose of Review This review summarizes the most recent evidence regarding the
effects of micronutrients on brain development. Recent Findings Emerging evidence …
effects of micronutrients on brain development. Recent Findings Emerging evidence …
The oncopig cancer model: an innovative large animal translational oncology platform
Despite an improved understanding of cancer molecular biology, immune landscapes, and
advancements in cytotoxic, biologic, and immunologic anti-cancer therapeutics, cancer …
advancements in cytotoxic, biologic, and immunologic anti-cancer therapeutics, cancer …
Ferroptosis induction in multiple myeloma cells triggers DNA methylation and histone modification changes associated with cellular senescence
Disease relapse and therapy resistance remain key challenges in treating multiple
myeloma. Underlying (epi-) mutational events can promote myelomagenesis and contribute …
myeloma. Underlying (epi-) mutational events can promote myelomagenesis and contribute …
Epigenetics and neurodegeneration: role of early-life nutrition
R Gabbianelli, E Damiani - The Journal of nutritional biochemistry, 2018 - Elsevier
Neurodegeneration represents a global problem due to the progressive increase in the
aging population all over the world. The quality of life in aging and the cost for the health …
aging population all over the world. The quality of life in aging and the cost for the health …
Early-life iron deficiency anemia programs the hippocampal epigenomic landscape
Iron deficiency (ID) anemia is the foremost micronutrient deficiency worldwide, affecting
around 40% of pregnant women and young children. ID during the prenatal and early …
around 40% of pregnant women and young children. ID during the prenatal and early …
The impact of maternal and early life malnutrition on health: a diet-microbe perspective
Background Early-life malnutrition may have long-lasting effects on microbe-host
interactions that affect health and disease susceptibility later in life. Diet quality and quantity …
interactions that affect health and disease susceptibility later in life. Diet quality and quantity …
Nurturing development: how a mother's nutrition shapes offspring's brain through the gut
Pregnancy is a transformative period marked by profound physical and emotional changes,
with far-reaching consequences for both mother and child. Emerging research has …
with far-reaching consequences for both mother and child. Emerging research has …
Maternal mineral nutrition regulates fetal genomic programming in cattle: A review
Maternal mineral nutrition during the critical phases of fetal development may leave lifetime
impacts on the productivity of an individual. Most research within the developmental origins …
impacts on the productivity of an individual. Most research within the developmental origins …
The molecular basis of p21-activated kinase-associated neurodevelopmental disorders: From genotype to phenotype
M Dobrigna, S Poëa-Guyon, V Rousseau… - Frontiers in …, 2023 - frontiersin.org
Although the identification of numerous genes involved in neurodevelopmental disorders
(NDDs) has reshaped our understanding of their etiology, there are still major obstacles in …
(NDDs) has reshaped our understanding of their etiology, there are still major obstacles in …