Procreation is essential for survival of species. Not surprisingly, complex neuronal networks
have evolved to mediate the diverse internal and external environmental inputs that regulate …

Kisspeptin (a product of the Kiss1 gene) and its receptor (GPR54 or Kiss1r) have emerged
as key players in the regulation of reproduction. Mutations in humans or genetically targeted …

Recently, a subset of neurons was identified in the arcuate nucleus of the hypothalamus that
colocalize three neuropeptides, kisspeptin, neurokinin B, and dynorphin, each of which has …

BACKGROUND The discovery of kisspeptin as key central regulator of GnRH secretion has
led to a new level of understanding of the neuroendocrine regulation of human reproduction …

In the past decade since kisspeptin/neurokinin B/dynorphin (KNDy) cells were first identified
in the mammalian hypothalamus, a plethora of new research has emerged adding insights …

Reproduction and fertility are regulated via hormones of the hypothalamic‐pituitary‐gonadal
(HPG) axis. Control of this reproductive axis occurs at all levels, including the brain and …

Kisspeptin signaling via the kisspeptin receptor G‐protein‐coupled receptor‐54 plays a
fundamental role in the onset of puberty and the regulation of mammalian reproduction. In …

Seasonality is an important adaptive trait in temperate fish species as it entrains or regulates
most physiological events such as reproductive cycle, growth profile, locomotor activity and …

Under stressful condition, reproductive function is impaired due to the activation of various
components of the hypothalamic–pituitaryadrenal (HPA) axis, which can suppress the …

Kisspeptin stimulates reproduction, and kisspeptin cells in the arcuate nucleus (ARC)
express Ob-Rb in the mouse. Herein we report studies in ewes to determine whether …