Angiogenesis plays a central role in human physiology from reproduction and fetal
development to wound healing and tissue repair/regeneration. Clinically relevant therapies …

The liver is a major organ that is involved in essential biological functions such as digestion,
nutrient storage, and detoxification. Furthermore, it is one of the most metabolically active …

Integrin β (ITGB) superfamily members have been reported to play important roles in
multiple biological functions in various cancers. However, the prognostic and oncologic …

Background: Cardiac hypertrophy is an important prepathology of, and will ultimately lead to,
heart failure. However, the mechanisms underlying pathological cardiac hypertrophy remain …

Diabetic retinopathy (DR) is a major complication of diabetes and a leading cause of
blindness and visual impairment. This study focuses on the function of lysine …

Ischemic cardiomyopathy seriously endangers human health leading to a poor prognosis.
Acute myocardial infarction (AMI) is the primary etiology, and the pathophysiological process …

Ischemia-induced angiogenesis is critical for blood flow restoration and tissue regeneration,
but the underlying molecular mechanism is not fully understood. ATG7 (autophagy related 7) …

Metabolism-related fatty liver disease (MAFLD) is associated with abnormal fat accumulation
in the liver. The exact mechanism underlying the occurrence and development of MAFLD …

Abnormal phenotypic switch, migration, and proliferation of vascular smooth muscle cells
(VSMCs) are hallmarks for pathogenesis of thoracic aortic dissection (TAD). In the current …

Osteosarcoma is the most common malignant bone tumor in adolescents, and metastasis is
the key reason for treatment failure and poor prognosis. Once metastasis occurs, the 5-year …