The Hierarchical Taxonomy of Psychopathology (HiTOP) has emerged out of the
quantitative approach to psychiatric nosology. This approach identifies psychopathology …

Fear and anxiety play a central role in mammalian life, and there is considerable interest in
clarifying their nature, identifying their biological underpinnings, and determining their …

Psychiatry has always been characterized by a range of different models of and approaches
to mental disorder, which have sometimes brought progress in clinical practice, but have …

Despite considerable progress in pharmacotherapy over the past seven decades, many
mental disorders remain insufficiently treated. This situation is in part due to the limited …

Abstract The Research Domain Criteria (RDoC) and the Hierarchical Taxonomy of
Psychopathology (HiTOP) represent major dimensional frameworks proposing two …

Generalization of conditioned fear is adaptive in some situations but maladaptive when fear
excessively generalizes to innocuous stimuli with incidental resemblance to a genuine …

The p-factor is a construct that is thought to explain and maybe even cause variation in all
forms of psychopathology. Since its 'discovery'in 2012, hundreds of studies have been …

Mental health research is at an important crossroads as the field seeks more reliable and
valid phenotypes to study. Dimensional approaches to quantifying mental illness operate …

In this article, we describe the collaborative process that is underway to develop measures
for the Hierarchical Taxonomy of Psychopathology (HiTOP). The HiTOP model has …

Neurodevelopmental disorders–including attention‐deficit/hyperactivity disorder (ADHD),
autism spectrum disorder, communication disorders, intellectual disability, motor disorders …