Challenges associated with interpreting mechanisms of AF

CH Roney, AL Wit, NS Peters - Arrhythmia & Electrophysiology …, 2019 - pmc.ncbi.nlm.nih.gov
Determining optimal treatment strategies for complex arrhythmogenesis in AF is confounded
by the lack of consensus regarding the mechanisms causing AF. Studies report different …

In silico Comparison of Left Atrial Ablation Techniques That Target the Anatomical, Structural, and Electrical Substrates of Atrial Fibrillation

CH Roney, ML Beach, AM Mehta, I Sim… - Frontiers in …, 2020 - frontiersin.org
Catheter ablation therapy for persistent atrial fibrillation (AF) typically includes pulmonary
vein isolation (PVI) and may include additional ablation lesions that target patient-specific …

Ventricular fibrillation mechanism and global fibrillatory organization are determined by gap junction coupling and fibrosis pattern

BS Handa, X Li, N Baxan, CH Roney… - Cardiovascular …, 2021 - academic.oup.com
Aims Conflicting data exist supporting differing mechanisms for sustaining ventricular
fibrillation (VF), ranging from disorganized multiple-wavelet activation to organized rotational …

Map** and ablation of ventricular fibrillation substrate

FM Ezzeddine, RC Ward, SJ Asirvatham… - Journal of Interventional …, 2023 - Springer
Ventricular fibrillation (VF) is a life-threatening arrhythmia and a common cause of sudden
cardiac death (SCD). A basic understanding of its mechanistic underpinning is crucial for …

Evaluation of the responsiveness pattern to caffeine through a smart data-driven ECG non-linear multi-band analysis

R Domingues, P Batista, M Pintado, P Oliveira-Silva… - Heliyon, 2024 - cell.com
This study aimed to explore more efficient ways of administering caffeine to the body by
investigating the impact of caffeine on the modulation of the nervous system's activity …

Vector of diagnostic features in the form of decomposition coefficients of statistical estimates using a cyclic random process model of cardiosignal

V Martsenyuk, A Sverstiuk… - 2019 10th IEEE …, 2019 - ieeexplore.ieee.org
The paper suggests the use of diagnostic features in the form of decomposition coefficients
of electrocardiograms statistical estimates in the normal range and in different types of …

Standardised framework for quantitative analysis of fibrillation dynamics

X Li, CH Roney, BS Handa, RA Chowdhury… - Scientific Reports, 2019 - nature.com
The analysis of complex mechanisms underlying ventricular fibrillation (VF) and atrial
fibrillation (AF) requires sophisticated tools for studying spatio-temporal action potential (AP) …

Granger causality–based analysis for classification of fibrillation mechanisms and localization of rotational drivers

BS Handa, X Li, KK Aras, NA Qureshi… - Circulation …, 2020 - ahajournals.org
Background: The mechanisms sustaining myocardial fibrillation remain disputed, partly due
to a lack of map** tools that can accurately identify the mechanism with low spatial …

[HTML][HTML] Fractional generalization of entropy improves the characterization of rotors in simulated atrial fibrillation

JP Ugarte, JAT Machado, C Tobón - Applied Mathematics and …, 2022 - Elsevier
Atrial fibrillation (AF) underlies disordered spatiotemporal electrical activity, that increases in
complexity with the persistence of the arrhythmia. It has been hypothesized that a specific …

Investigation of the role of myocyte orientations in cardiac arrhythmia using image-based models

DG Whittaker, AP Benson, I Teh, JE Schneider… - Biophysical …, 2019 - cell.com
Cardiac electrical excitation-propagation is influenced by myocyte orientations (cellular
organization). Quantitatively understanding this relationship presents a significant research …