Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …
The biology, function, and biomedical applications of exosomes
BACKGROUND All cells, prokaryotes and eukaryotes, release extracellular vesicles (EVs)
as part of their normal physiology and during acquired abnormalities. EVs can be broadly …
as part of their normal physiology and during acquired abnormalities. EVs can be broadly …
Engineered neutrophil-derived exosome-like vesicles for targeted cancer therapy
Neutrophils are the most abundant innate immune cells in human circulation; however, their
derived exosomes have been rarely studied for tumor treatment. Here, we reported that …
derived exosomes have been rarely studied for tumor treatment. Here, we reported that …
[HTML][HTML] Engineering exosomes for targeted drug delivery
Exosomes are cell-derived nanovesicles that are involved in the intercellular transportation
of materials. Therapeutics, such as small molecules or nucleic acid drugs, can be …
of materials. Therapeutics, such as small molecules or nucleic acid drugs, can be …
Exosome: a review of its classification, isolation techniques, storage, diagnostic and targeted therapy applications
Y Zhang, J Bi, J Huang, Y Tang, S Du… - International journal of …, 2020 - Taylor & Francis
Exosomes are nano-sized small extracellular vesicles secreted by cells, carrying nucleic
acids, proteins, lipids and other bioactive substances to play a role in the body's …
acids, proteins, lipids and other bioactive substances to play a role in the body's …
Exosomes: composition, biogenesis, and mechanisms in cancer metastasis and drug resistance
Tumor-derived exosomes (TDEs) participate in formation and progression of different cancer
processes, including tumor microenvironment (TME) remodeling, angiogenesis, invasion …
processes, including tumor microenvironment (TME) remodeling, angiogenesis, invasion …
Prevalence and disease burden of chronic kidney disease
JC Lv, LX Zhang - Renal fibrosis: mechanisms and therapies, 2019 - Springer
Chronic kidney disease (CKD) has been recognized as a leading public health problem
worldwide. The global estimated prevalence of CKD is 13.4%(11.7–15.1%), and patients …
worldwide. The global estimated prevalence of CKD is 13.4%(11.7–15.1%), and patients …
Extracellular vesicles in cancer—implications for future improvements in cancer care
The sustained growth, invasion, and metastasis of cancer cells depend upon bidirectional
cell–cell communication within complex tissue environments. Such communication …
cell–cell communication within complex tissue environments. Such communication …
Review of the isolation, characterization, biological function, and multifarious therapeutic approaches of exosomes
Exosomes are extracellular vesicles that contain a specific composition of proteins, lipids,
RNA, and DNA. They are derived from endocytic membranes and can transfer signals to …
RNA, and DNA. They are derived from endocytic membranes and can transfer signals to …
[HTML][HTML] Extracellular vesicles as drug delivery systems: Why and how?
OM Elsharkasy, JZ Nordin, DW Hagey… - Advanced drug delivery …, 2020 - Elsevier
Over the past decades, a multitude of synthetic drug delivery systems has been developed
and introduced to the market. However, applications of such systems are limited due to …
and introduced to the market. However, applications of such systems are limited due to …