ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation task force on expert consensus …
Writing Committee Members, VV McLaughlin… - Circulation, 2009 - Am Heart Assoc
ACCF/AHA 2009 Expert Consensus Document on Pulmonary Hypertension | Circulation Science
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Cellular and molecular pathobiology of pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) has a multifactorial pathobiology. Vasoconstriction,
remodeling of the pulmonary vessel wall, and thrombosis contribute to increased pulmonary …
remodeling of the pulmonary vessel wall, and thrombosis contribute to increased pulmonary …
Treatment of pulmonary arterial hypertension
M Humbert, O Sitbon… - New England Journal of …, 2004 - Mass Medical Soc
Pulmonary arterial hypertension, which is characterized by vascular proliferation and
remodeling of small pulmonary vessels, leads to a progressive increase in pulmonary …
remodeling of small pulmonary vessels, leads to a progressive increase in pulmonary …
Pulmonary hypertension
Pulmonary hypertension encompasses a range of conditions directly or indirectly leading to
elevated pressures within the pulmonary arteries. Five main groups of pulmonary …
elevated pressures within the pulmonary arteries. Five main groups of pulmonary …
[HTML][HTML] Mechanisms of disease: pulmonary arterial hypertension
RT Schermuly, HA Ghofrani, MR Wilkins… - Nature Reviews …, 2011 - nature.com
Our understanding of, and approach to, pulmonary arterial hypertension has undergone a
paradigm shift in the past decade. Once a condition thought to be dominated by increased …
paradigm shift in the past decade. Once a condition thought to be dominated by increased …
Molecular genetic framework underlying pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is a rare, progressive disorder typified by occlusion
of the pulmonary arterioles owing to endothelial dysfunction and uncontrolled proliferation of …
of the pulmonary arterioles owing to endothelial dysfunction and uncontrolled proliferation of …
A novel channelopathy in pulmonary arterial hypertension
L Ma, D Roman-Campos, ED Austin… - … England Journal of …, 2013 - Mass Medical Soc
Background Pulmonary arterial hypertension is a devastating disease with high mortality.
Familial cases of pulmonary arterial hypertension are usually characterized by autosomal …
Familial cases of pulmonary arterial hypertension are usually characterized by autosomal …
Adaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2
NR Prabhakar, GL Semenza - Physiological reviews, 2012 - journals.physiology.org
Hypoxia is a fundamental stimulus that impacts cells, tissues, organs, and physiological
systems. The discovery of hypoxia-inducible factor-1 (HIF-1) and subsequent identification of …
systems. The discovery of hypoxia-inducible factor-1 (HIF-1) and subsequent identification of …
Primary pulmonary hypertension
SP Gaine, LJ Rubin - The Lancet, 1998 - thelancet.com
Primary pulmonary hypertension (PPH) is a progressive disease characterised by raised
pulmonary vascular resistance, which results in diminished right-heart function due to …
pulmonary vascular resistance, which results in diminished right-heart function due to …
Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies
Pulmonary arterial hypertension (PAH) is a syndrome in which pulmonary arterial
obstruction increases pulmonary vascular resistance, which leads to right ventricular (RV) …
obstruction increases pulmonary vascular resistance, which leads to right ventricular (RV) …