Biological phase separation is known to be important for cellular organization, which has
recently been extended to a new class of biomolecules that form liquid-like droplets …

Malignant transformation is characterized by dysregulation of diverse cellular processes that
have been the subject of detailed genetic, biochemical, and structural studies, but only …

Various physics-and data-driven sequence-dependent protein coarse-grained models have
been developed to study biomolecular phase separation and elucidate the dominant …

Many intrinsically disordered proteins (IDPs) may undergo liquid–liquid phase separation
(LLPS) and participate in the formation of membraneless organelles in the cell, thereby …

Temperature controls plant growth and development, and climate change has already
altered the phenology of wild plants and crops. However, the mechanisms by which plants …

Prion-like low-complexity domains (PLCDs) have distinctive sequence grammars that
determine their driving forces for phase separation. Here we uncover the physicochemical …

Many cellular proteins demix spontaneously from solution to form liquid condensates. These
phase-separated structures have wide-ranging roles in health and disease. Elucidating the …

Biomolecular condensates, membrane-less entities arising from liquid–liquid phase
separation, hold dichotomous roles in health and disease. Alongside their physiological …

Biomolecular condensates, formed through phase separation, are upending our
understanding in much of molecular, cell, and developmental biology. There is an urgent …

Phase separation of intrinsically disordered proteins (IDPs) commonly underlies the
formation of membraneless organelles, which compartmentalize molecules intracellularly in …