The dynamic lung microbiome in health and disease

JG Natalini, S Singh, LN Segal - Nature Reviews Microbiology, 2023 - nature.com
New methods and technologies within the field of lung biology are beginning to shed new
light into the microbial world of the respiratory tract. Long considered to be a sterile …

Definition, causes, pathogenesis, and consequences of chronic obstructive pulmonary disease exacerbations

AI Ritchie, JA Wedzicha - Clinics in chest medicine, 2020 - chestmed.theclinics.com
Acute exacerbations of chronic obstructive pulmonary disease (AECOPDs) are episodes of
symptom worsening 1 that have significant adverse consequences for patients. 2 The …

The influence of the microbiome on respiratory health

TP Wypych, LC Wickramasinghe, BJ Marsland - Nature immunology, 2019 - nature.com
The revolution in microbiota research over the past decade has provided invaluable
knowledge about the function of the microbial species that inhabit the human body. It has …

The lung microbiome: progress and promise

SA Whiteside, JE McGinniss… - The Journal of Clinical …, 2021 - Am Soc Clin Investig
The healthy lung was long thought of as sterile, but recent advances using molecular
sequencing approaches have detected bacteria at low levels. Healthy lung bacteria largely …

Oral microbiome and SARS-CoV-2: beware of lung co-infection

L Bao, C Zhang, J Dong, L Zhao, Y Li… - Frontiers in microbiology, 2020 - frontiersin.org
The new coronavirus SARS-CoV-2, the cause of COVID-19, has become a public health
emergency of global concern. Like the SARS and influenza pandemics, there have been a …

The lung microbiome during health and disease

K Yagi, GB Huffnagle, NW Lukacs, N Asai - International journal of …, 2021 - mdpi.com
Healthy human lungs have traditionally been considered to be a sterile organ. However,
culture-independent molecular techniques have reported that large numbers of microbes …

Lung microbiome: new insights into the pathogenesis of respiratory diseases

R Li, J Li, X Zhou - Signal transduction and targeted therapy, 2024 - nature.com
The lungs were long thought to be sterile until technical advances uncovered the presence
of the lung microbial community. The microbiome of healthy lungs is mainly derived from the …

Smoking and microbiome in oral, airway, gut and some systemic diseases

C Huang, G Shi - Journal of translational medicine, 2019 - Springer
The human microbiome harbors a diverse array of microbes which establishes a mutually
beneficial relation with the host in healthy conditions, however, the dynamic homeostasis is …

Unexpected guests in the tumor microenvironment: microbiome in cancer

A Wong-Rolle, HK Wei, C Zhao, C ** - Protein & cell, 2021 - academic.oup.com
Although intestinal microbiome have been established as an important biomarker and
regulator of cancer development and therapeutic response, less is known about the role of …

The human microbiome in disease and pathology

J Manos - Apmis, 2022 - Wiley Online Library
This narrative review seeks to examine the relationships between bacterial microbiomes
and infectious disease. This is achieved by detailing how different human host microbiomes …